Research Scholar
NCIRE - The Northern California Institute for Research and Education, Inc.
Summary
A postdoctoral scholar (Ph.D., M.D., or M.D./Ph.D.) is needed to advance projects to investigate the mechanisms, primarily in the human airway, that allow respiratory pathogens, particularly fungal pathogens, to cause disease. These projects involve implementing and developing laboratory assays to apply to samples from infected and uninfected individuals, as well as the culture and manipulation of fungal pathogens at BSL2 and/or BSL3. This position is in training with the Principal Investigator to prepare for a career in human immunology in academia or industry.
Job description
Essential Functions
- Assist in maintaining and monitoring all equipment and procedures for quality control
- Review pertinent medical literature
- Design and execute experiments using cellular, biochemical, and molecular biology techniques
- Process human biological samples, including isolation of cells from blood and tissues; store and ship samples as needed
- Perform molecular biology procedures, including DNA and RNA isolation, reverse transcription, PCR, qPCR and qRT-PCR, ELISA, FISH, single-cell capture, sequencing library prep, and possibly others.
- Perform cell culture procedures, including culture of cell lines and primary cells, transfection, in vitro infection, fluorescent microscopy, flow cytometry, single cell analysis methods, and possibly other techniques
- Implement, troubleshoot, optimize, and develop new assays, making innovative contributions to laboratory procedures
- Assist with the training of research methods and approaches to the laboratory group
- Maintain a detailed written record of work performed
- Perform analysis of experiment results and findings, including data collection, entry, statistical analysis (including computational analysis of sequencing data using R and/or Python), and graph creation
- Produce written reports detailing results of experiments and analysis of results, and draft manuscripts of results for publication
- Present oral and/or poster reports at laboratory, local, and national meetings
- Assist with the composition of grant applications
- Adhere to data security requirements
- Perform other duties as assigned
Job Requirements
- PhD in microbiology, immunology, or related science, MD, MD/PhD, or equivalent combination of education and experience
- 2+ years of related work experience desirable
- Knowledge of principles and practice of cellular and molecular biology
- Working knowledge of safety standards in laboratories
- Solid interpersonal skills
- Excellent organizational skills
- Careful attention to detail; ability to accurately follow experimental protocols
- Ability to manage multiple projects, tasks, and priorities to achieve desired goals
- Ability to meet deadlines
- Ability to think creatively and solve problems
- Ability to work under minimal supervision
- Strong written/oral communication skills
- Computer literacy with full working knowledge of MS Word/ or Overleaf/LaTeX or markdown, Excel, PowerPoint/Keynote, R, and graphing software
- Ability to analyze data and perform statistical analyses.
- Ability to make sound decisions consistent with the essential job functions.
Working Conditions/Environment
The work environment is a biomedical research laboratory. It may include minor annoyances such as noise, temperature variations, etc. The incumbent may be required to sustain standing and seated postures and to use a computer keyboard and display monitor for prolonged periods.
Requirements
- PhD in microbiology, immunology, or related science, MD, MD/PhD, or equivalent combination of education and experience
- 2+ years of related work experience desirable
- Knowledge of principles and practice of cellular and molecular biology
- Working knowledge of safety standards in laboratories
- Solid interpersonal skills
- Excellent organizational skills
- Careful attention to detail; ability to accurately follow experimental protocols
- Ability to manage multiple projects, tasks, and priorities to achieve desired goals
- Ability to meet deadlines
- Ability to think creatively and solve problems
- Ability to work under minimal supervision
- Strong written/oral communication skills
- Computer literacy with full working knowledge of MS Word/ or Overleaf/LaTeX or markdown, Excel, PowerPoint/Keynote, R, and graphing software
- Ability to analyze data and perform statistical analyses.
- Ability to make sound decisions consistent with the essential job functions.
Company overview
NCIRE - The Northern California Institute for Research and Education, Inc. is the leading private nonprofit research institute in the United States exclusively dedicated to advancing Veterans' health research. Founded in 1988 and operating as a 501(c)(3) nonprofit organization, NCIRE partners with the San Francisco VA Health Care System (SFVAHCS) and the University of California San Francisco (UCSF) to conduct groundbreaking biomedical research. The institute supports over 200 MD and PhD principal investigators working across diverse research areas including Alzheimer's disease, cancer, cardiovascular disease, mental health, post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and substance use disorders. With $70 million in research expenditures, NCIRE manages the largest funded research program within the Veterans Health Administration, operating from 250,000-300,000 square feet of research space on the SFVAHCS campus. The organization's mission focuses on improving health outcomes for Veterans and active military personnel through innovative scientific discoveries, clinical trials, and translational research that bridges laboratory findings to clinical applications.