Researcher in transcription regulation
Department of Pharmacy, University of Copenhagen
Summary
The Researcher's responsibilities will primarily consist of research, including publication/academic dissemination duties, and research-based teaching and mentorship, primarily in a laboratory setting.
Job description
Your job
The Researcher's responsibilities will primarily consist of research, including publication/academic dissemination duties, and research-based teaching and mentorship, primarily in a laboratory setting.
The project will be decided in consultation with the selected candidate(s) in accordance with ongoing research programmes within the individual groups. Broadly, projects are focused on understanding the various aspects of the process of gene expression, ranging from the mechanisms of 3D chromatin organisation to transcription, mRNA processing, translation, and protein turnover.
Essential Experience and Skills
- PhD in life science
- Research qualifications at the level that can be achieved by satisfactorily completing a period of employment as a postdoc but may also be obtained in other ways
- Research-based teaching or mentorship
- Highly experienced in either biochemistry, molecular cell biology, genome-wide analysis, or quantitative imaging in mammalian cells
- Previous experience within the field of transcription and/or co-transcriptional processing, ideally with a focus on RNAPII regulation
- High degree of independence, motivation, attention to detail and proactiveness
- Excellent time-management, self-organisation and teamwork skills
- Problem-solving mindset, strong communication skills, and a collaborative spirit
Desirable Experience and Skills
- Experience with CRISPR/Cas9 genome editing and/or screening approaches
- Experience with techniques to profile nascent transcription, RNAPII occupancy, ribosome footprinting, etc.
- Experience with proteomics to characterise RNAPII elongation complexes
- Excellent skills in written and spoken English
- Ability to communicate in Danish is preferable
Requirements
- PhD in life science
- Research qualifications at the level achieved through a postdoc period
- Research-based teaching or mentorship experience
- Highly experienced in biochemistry, molecular cell biology, genome-wide analysis, or quantitative imaging in mammalian cells
- Previous experience in transcription and/or co-transcriptional processing, ideally RNAPII regulation
- High degree of independence, motivation, attention to detail and proactiveness
- Excellent time-management, self-organisation and teamwork skills
- Problem-solving mindset, strong communication skills, and collaborative spirit
- Excellent written and spoken English
Benefits
- Pension Contribution
- Tax Reduction Eligibility
- International Research Environment
- State-of-the-Art Facilities
Company overview
The Department of Pharmacy at the University of Copenhagen is a premier academic institution dedicated to pharmaceutical education and cutting-edge research in pharmaceutical sciences. As part of Denmark's oldest and most prestigious university, the department focuses on advancing pharmaceutical analytical chemistry, drug development, and pharmaceutical technology. It houses the Center for Advanced Drug Analysis (CADA), which combines three specialized research groups: Pharmaceutical Analytical Chemistry, Drug Toxicology, Metabolism and Analysis, and Protein Analysis Group. The department offers comprehensive bachelor's, master's, and PhD programs in pharmaceutical sciences, providing students with rigorous theoretical training and hands-on laboratory experience. Research activities span modern analytical chemistry techniques including liquid chromatography-mass spectrometry, capillary electrophoresis, microfluidics, and mass spectrometry imaging for drug analysis. The department maintains strong collaborations with pharmaceutical industry partners such as Novo Nordisk, Roche, and Biogen, facilitating translational research and student opportunities. With a focus on both fundamental pharmaceutical research and applied drug development, the Department of Pharmacy plays a crucial role in training the next generation of pharmaceutical scientists and advancing pharmaceutical innovation in Denmark and internationally.