Scientist, Bioconjugate Analytics - Analytical and Biological Mass Spectrometry (ABMS)

Build our future together

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Scientist to join the Bioconjugate Analytics (BCA) team within the Analytical and Biological Mass Spectrometry (ABMS) Group. In this role, you will develop and apply LC-MS-based analytical methods to advance Regeneron's bioconjugate pipeline across all stages of development, including antibody-drug conjugates (ADCs), antibody-oligonucleotide conjugates (AOCs), antibody-tethered ligands (ATLs), and other emerging bioconjugate modalities.

Discover your role

• Develop and apply LC-MS-based analytical methods to characterize bioconjugates and other therapeutic protein candidates across R&D programs
• Perform sample preparation, LC-MS experiments, and data analysis using relevant software and bioinformatics tools to characterize product quality attributes; document results in electronic laboratory notebook (ELN) entries, presentations, and reports
• Support process development, R&D activities, and regulatory submissions through analytical characterization and scientific problem-solving
• Collaborate with cross-functional teams to understand analytical needs, coordinate samples and study activities, and align priorities, timelines, and deliverables
• Interpret and communicate scientific results through project and group meetings, technical reports, regulatory documents, internal and external conferences, and peer-reviewed publications
• Bring strong knowledge of and hands-on experience with LC-MS-based characterization of proteins, peptides, and bioconjugates (e.g., ADCs, AOCs, and ATLs), including sample preparation, liquid chromatography, mass spectrometry, and data analysis
• Develop and troubleshoot analytical methods and solve complex scientific and technical problems
• Collaborate cross-functionally as a strong communicator, building productive working relationships and coordinating samples, activities, priorities, timelines, and deliverables across multiple programs
• Bring a results-driven, highly organized, and adaptable approach, with scientific curiosity and the ability to learn new technologies and thrive in an innovative, fast-paced, and collaborative R&D environment

This role requires

• Master's degree with at least 6 years of relevant experience, or a Bachelor's degree with at least 8 years of relevant experience, in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field
• Industrial or academic experience in analytical characterization of protein therapeutics, bioconjugates, or other therapeutic modalities
• Experience with advanced mass spectrometer platforms (e.g., Orbitrap, Q-TOF, and triple quadrupole), liquid chromatography, and relevant data processing software (e.g., Protein Metrics, ChemDraw, Skyline, Proteome Discoverer, Compound Discoverer, and other related analytical tools) is highly desired