Scientist, Drug Product Development and Technology (DPDT)

When & where:

• Shift Requirements: Full-Time, Onsite 4 Days per week
• Location: Tarrytown, NY

What you’ll do:

• Conduct R&D evaluations of innovative drug delivery technologies that address business needs and challenges across key therapeutic areas
• Assess pharmaceutical delivery technologies and systems at various development stages, and support formulation and characterization studies for new technology development
• Support the development and evaluation of drug and gene delivery technologies across modalities, including monoclonal antibodies, fusion proteins, and RNA therapeutics
• Design and support formulation, process, analytical, and device characterization studies across multiple new technology development initiatives
• Design and execute robust experiments to evaluate LNPs and RNA-based therapeutics, including formulation development, characterization, and scale-up activities
• Support evaluation of novel excipients (including viscosity-reducing agents, surfactants, and preservatives), drug delivery approaches (including sustained-release, alternative routes of administration, and high-concentration formulations), and novel drug-device combination products
• Work and collaborate in cross-functional teams to support research, formulation, analytical activities, process development, toxicology, and PK/PD studies
• Take accountability for project execution, deliverables (including study protocols and reports), and timelines
• Compile and interpret data, and communicate findings through presentations and technical reports
• Prepare data presentations and communicate results in cross-functional team meetings, department meetings, and to management

Let’s find out if we’re a fit:

Must-haves:

• Master’s degree with 6+ years, or Bachelor’s degree with 8+ years, of relevant experience in Pharmaceutical Sciences, Biotechnology, Biomedical Engineering, Chemical Engineering, Chemistry, Biology, or a related field
• Experience and solid understanding of biologics formulation, analytics, and process development (e.g., genetic medicine, drug delivery technologies)
• Understanding of statistical approaches and software packages for data analysis and design of experiments (DOE) for analytical method development and/or formulation development
• Strong scientific and organizational skills, with the ability to work efficiently within a team
• Demonstrated ability to think creatively, develop solutions to complex and varied problems, and deliver productive, insightful analyses and outcomes
• Strong initiative and drive to complete ambitious tasks and proactively learn new technologies
• Excellent oral and written communication skills, with demonstrated experience in scientific writing (abstracts, publications) and/or conference presentations

Preferred / nice-to-haves:

• Hands-on experience in biologics/genetic medicine product development, including formulation, process, and characterization fundamentals
• Consistent record of handling a variety of analytical techniques for diverse therapeutic modalities (e.g., mAbs, oligonucleotides)
• Hands-on experience with DLS, Ribogreen assay, microfluidics mixing, TFF, cell culture, HPLC/UPLC, UV-Vis, fluorescence, viscometer, chromatography, electrophoresis (cIEF, MCE-SDS, SDS-PAGE), imaging/microscopy techniques (MFI, SEM), and other analytical techniques relevant for biologics characterization
• Understanding of genetic medicine, such as RNA and lipid nanoparticles
• Experience applying machine learning and molecular simulation to novel excipient design and development