St. Jude Children's Research Hospital logo

Scientist (Genomics / Gene Editing & Bioinformatics) - Wlodarski Lab

St. Jude Children's Research Hospital

Memphis, TNOnsitePosted 13 days ago$86,320 - $154,960/year
Full TimeSenior LevelResearch & ScientistResearch Institute
Original posting ↗

Summary

The Scientist independently designs, performs, and coordinates a broad range of advanced laboratory and computational research activities supporting cutting-edge genomics programs focused on hematologic disorders and cancer predisposition. Research efforts span multi-omics studies (genomics, transcriptomics, epigenomics) and genome editing. Particular emphasis is on characterizing novel genes and clonal lesions that drive clonal evolution, and on developing therapeutic base-editing strategies.

Job description

The Scientist develops and executes experimental strategies integrating both wet lab techniques and bioinformatics analyses, contributing to projects that span discovery through data interpretation. This role requires the ability to analyze, interpret, and present complex biological datasets, while actively contributing to experimental design, protocol development, and scientific reporting.

The ideal candidate brings primary expertise in either wet lab biology or computational biology, along with working knowledge of the complementary discipline (e.g., wet lab scientists with bioinformatics exposure, or computational scientists with hands-on laboratory experience), enabling effective collaboration across interdisciplinary teams.

Job Responsibilities

  • Design, coordinate, and execute research projects involving genetics/genomics, including gene editing technologies (e.g., CRISPR-Cas9 and base editing) and downstream analysis
  • Perform laboratory experiments and apply appropriate techniques; evaluate methodologies and recommend alternative approaches or tools as needed
  • Conduct bioinformatics and computational analyses of genomic datasets, including processing, organization, interpretation, and visualization of data
  • Contribute to the development, optimization, and implementation of new laboratory and computational protocols
  • Identify and extract relevant experimental data; ensure accuracy, quality, and integrity of datasets and analyses
  • Summarize and communicate research findings through reports, presentations, and contributions to manuscripts/publications
  • Support laboratory operations, including equipment maintenance, calibration and troubleshooting
  • Maintain inventory and ensure proper functioning of laboratory and computational resources
  • Train and mentor staff or junior researchers in laboratory techniques, data analysis methods, and best practices

Minimum Education and/or Training

  • Bachelor's degree in relevant scientific area is required

Minimum Experience

  • Eight (8) years of relevant work experience is required
  • Six (6) years of relevant work experience is required with a Master's degree
  • Three (3) years of relevant work experience is required with a PhD

Preferred Qualifications

  • Strong experience in genetics/genomics and gene editing technologies (CRISPR-Cas9, base editing, prime editing)
  • Proven experience in bioinformatics or computational biology, particularly genomic data analysis
  • A combination of wet lab and computational expertise
  • Demonstrated track record of scientific contributions (e.g., publications, project leadership, or impactful research outcomes)

Requirements

  • Bachelor's degree in relevant scientific area
  • Eight (8) years of relevant work experience
  • Six (6) years of relevant work experience with a Master's degree
  • Three (3) years of relevant work experience with a PhD
  • Strong experience in genetics/genomics and gene editing technologies (CRISPR-Cas9, base editing, prime editing)
  • Proven experience in bioinformatics or computational biology, particularly genomic data analysis
  • A combination of wet lab and computational expertise
  • Demonstrated track record of scientific contributions

Benefits

  • Comprehensive benefits package

Company overview

St. Jude Children's Research Hospital is a world-renowned pediatric research and treatment institution headquartered in Memphis, Tennessee, dedicated to advancing cures for childhood cancer and other catastrophic diseases. Founded in 1962 by entertainer Danny Thomas, it stands as the first and only National Cancer Institute-designated Comprehensive Cancer Center devoted exclusively to children. The hospital operates on a unique funding model where families never receive bills for treatment, travel, housing, or food, with costs exceeding $2 billion annually primarily supported by donations through its fundraising organization ALSAC. St. Jude treats approximately 8,600 patients each year from all 50 states and around the world, with a focus on acute lymphoblastic leukemia, brain tumors, sickle cell disease, and infectious diseases. The institution employs over 7,000 staff members and maintains eight affiliate clinics across the United States. Through its St. Jude Global initiative, the hospital shares research and treatment protocols internationally, partnering with more than 350 institutions in over 90 countries. St. Jude has been instrumental in increasing childhood cancer survival rates from 20% in 1962 to over 80% today, while maintaining a robust research program that includes gene therapy, bone marrow transplantation, and precision medicine approaches.

Explore more jobs of your matchFind more biopharma roles with GetBioJob.