Scientist II/III, LCMS Method Development
Pharmaron
Summary
Pharmaron is seeking a Scientist II/III, LCMS Method Development to join our growing Bioanalytical Sciences team in Exton, PA. In this role, you will contribute to the development and validation of innovative bioanalytical methods supporting drug discovery and development programs across a diverse range of therapeutic modalities, including small molecules, peptides, oligonucleotides, PROTACs, biologics, and emerging therapies.
Job description
Job Overview
Pharmaron is seeking a Scientist II/III, LCMS Method Development to join our growing Bioanalytical Sciences team in Exton, PA. In this role, you will contribute to the development and validation of innovative bioanalytical methods supporting drug discovery and development programs across a diverse range of therapeutic modalities, including small molecules, peptides, oligonucleotides, PROTACs, biologics, and emerging therapies.
Key Responsibilities
- Independently develop, optimize, validate, and troubleshoot LC-MS/MS bioanalytical methods.
- Design scientifically sound studies that meet sponsor and internal objectives.
- Execute and support bioanalytical testing for DMPK and regulated studies.
- Perform sample analysis using HPLC and LC-MS/MS platforms in compliance with developmental and GLP requirements.
- Review and execute study protocols governing bioanalytical studies and sample analysis.
- Process, analyze, interpret, and report study data.
- Author protocols, validation reports, technical summaries, and study reports.
- Support regulatory submissions through high-quality scientific documentation.
- Serve as Principal Investigator (PI) and/or Study Director (SD) within areas of expertise.
- Actively identify and resolve technical challenges while driving continuous improvement.
- Collaborate with scientists, project teams, management, business development, and clients to ensure successful project execution.
- Participate in project review meetings and compliance-related initiatives.
What We're Looking For
- Bachelor's degree in Pharmaceutical Sciences, Chemistry, Life Sciences, or a related scientific discipline.
- Scientist II: Minimum 2 years of bioanalytical testing experience.
- Scientist III: Minimum 4 years of bioanalytical testing experience.
- Experience supporting development and/or GLP-regulated bioanalytical studies.
- Strong understanding of HPLC and LC-MS/MS methodologies.
- Excellent analytical thinking, troubleshooting, and organizational skills.
- Ability to thrive in a fast-paced, collaborative, and matrixed environment.
Preferred Qualifications
- Experience with LC-MS/MS method development and validation.
- Experience analyzing peptides, oligonucleotides, PROTACs, and complex biologics.
- Familiarity with DMPK studies and regulated bioanalysis.
- Experience authoring scientific reports and supporting regulatory submissions.
- Prior CRO, pharmaceutical, or biotechnology industry experience.
- Experience serving in client-facing scientific roles.
Requirements
- Bachelor's degree in Pharmaceutical Sciences, Chemistry, Life Sciences, or a related scientific discipline.
- Scientist II: Minimum 2 years of bioanalytical testing experience.
- Scientist III: Minimum 4 years of bioanalytical testing experience.
- Experience supporting development and/or GLP-regulated bioanalytical studies.
- Strong understanding of HPLC and LC-MS/MS methodologies.
- Excellent analytical thinking, troubleshooting, and organizational skills.
- Ability to thrive in a fast-paced, collaborative, and matrixed environment.
Benefits
- Medical, Dental & Vision
- 401(k) Matching
- Generous PTO
- Paid Sick Leave
- Company Holidays
- Health Savings Account
- Flexible Spending Accounts
- Life Insurance
- AD&D Insurance
- Short-Term Disability
- Long-Term Disability
- Employee Assistance Program
- Fertility Support
- Maternity Resources
- Professional Development
Company overview
Pharmaron is a premier global life sciences service provider founded in 2004, offering comprehensive research, development, and manufacturing services throughout the entire drug discovery and development process. As a leading Contract Research Organization (CRO) and Contract Development and Manufacturing Organization (CDMO), Pharmaron provides integrated solutions across multiple therapeutic modalities including small molecules, biologics, and cell and gene therapy (CGT) products. The company's extensive service portfolio encompasses synthetic and medicinal chemistry, biology services, DMPK (drug metabolism and pharmacokinetics), pharmacology, toxicology, radiochemistry, CMC (chemistry, manufacturing, and controls), and clinical development services. With over 10,000 employees worldwide and facilities across China, the United States, and Europe, Pharmaron supports pharmaceutical and biotechnology companies in accelerating their R&D programs from early discovery through commercial manufacturing. The company is publicly listed on both the Shenzhen and Hong Kong stock exchanges and maintains a strong commitment to scientific excellence, regulatory compliance, and technological innovation in the life sciences sector.