Scientist II, Immunology
Vaxart
Summary
We are seeking a highly motivated, Scientist I/II to join our Immunology team. This individual will lead clinical and preclinical immunology studies supporting the advancement of our mucosal vaccine platform generating data that informs key research and development decisions.
Job description
Summary
We are seeking a highly motivated, Scientist I/II to join our Immunology team. This individual will lead clinical and preclinical immunology studies supporting the advancement of our mucosal vaccine platform generating data that informs key research and development decisions.
Responsibilities
- Independently design, optimize, execute and analyze cellular and humoral immunology assays including multiparameter flow cytometry (10+ colors), MesoScale Discovery (MSD), and neutralization assays using human biospecimens.
- Design and optimize ex vivo immune profiling studies using human PBMCs and other clinical samples.
- Lead and manage external and internal in-vitro and in-vivo pre-clinical studies.
- Develop and optimize laboratory methods and SOPs.
- Maintain detailed experimental records and ensure data integrity and reproducibility.
- Collaborate cross-functionally with Research and Clinical teams to achieve project goals.
- Contributes to scientific publications, regulatory documents, and grant applications.
- Present scientific findings, project updates, and strategic recommendations to multidisciplinary teams.
Requirements
- PhD in Immunology, Cell Biology, or relevant discipline.
- Strong understanding of cellular immunology and humoral responses, particularly in the context of infectious disease and/or vaccination.
- Extensive experience designing, executing and interpreting multiparameter flow cytometry.
- Strong understanding of human immune cell immunophenotyping and functional assays, including activation-induced marker (AIM) and memory T cell analysis.
- Experience working with clinical samples in a regulated or industry environment preferred.
- Proficiency using FlowJo, GraphPad Prism and Microsoft Office software.
- Excellent written and verbal communication skills, including experience presenting scientific data to diverse audiences.
- Strong interpersonal communication and organization skills with exceptional attention to detail.
- Ability to work on-site at our laboratory in South San Francisco, CA.
Requirements
- PhD in Immunology, Cell Biology, or relevant discipline
- Strong understanding of cellular immunology and humoral responses, particularly in the context of infectious disease and/or vaccination
- Extensive experience designing, executing and interpreting multiparameter flow cytometry
- Strong understanding of human immune cell immunophenotyping and functional assays, including activation-induced marker (AIM) and memory T cell analysis
- Experience working with clinical samples in a regulated or industry environment preferred
- Proficiency using FlowJo, GraphPad Prism and Microsoft Office software
- Excellent written and verbal communication skills, including experience presenting scientific data to diverse audiences
- Strong interpersonal communication and organization skills with exceptional attention to detail
- Ability to work on-site at our laboratory in South San Francisco, CA
Benefits
- Health plan options
- Bonus program
- Stock options
- 401(k) with employer matching
- Tuition assistance
- Commuter benefits
- Work-life balance
Company overview
Vaxart is a clinical-stage biotechnology company focused on developing oral recombinant vaccines administered using room-temperature-stable tablets. The company's innovative platform technology aims to transform vaccine delivery by creating convenient, needle-free alternatives to traditional injectable vaccines. Vaxart's lead programs include oral vaccine candidates for norovirus, influenza, and COVID-19, leveraging their proprietary vector and adjuvant technologies. The company's approach seeks to stimulate both mucosal and systemic immune responses, potentially offering broader protection against respiratory and gastrointestinal pathogens. Vaxart's technology platform represents a significant advancement in vaccine administration, addressing challenges related to cold chain logistics, healthcare worker burden, and patient compliance. The company continues to advance its pipeline through clinical development and strategic partnerships in the global vaccine market.