Scientist Immunology
Biogen
Summary
We are seeking a highly motivated and accomplished Scientist with drug discovery experience in diseases with an inflammatory etiology to join our growing Immunology team. The ideal candidate will have a strong background in immunology, cellular and molecular biology and/or related scientific field and contribute to the discovery and development of novel therapies targeting inflammatory and autoimmune disorders. This role offers an exciting opportunity to work in a dynamic, multidisciplinary environment at the nexus of basic research and therapeutic innovation to develop transformative therapies aimed at addressing unmet medical needs for patients who need it most.
Job description
Key Responsibilities
- Conceive, design and execute in vitro and in vivo studies to explore mechanisms underlying inflammatory and autoimmune diseases
- Identify and validate new drug targets, biomarkers, and pathways relevant to immune-mediated disorders
- Generate data that supports lead optimization, biomarker discovery, and translational research
- Generate and interpret complex data sets and present findings internally and externally (e.g. meetings, conferences, publications)
- Collaborate cross-functionally with colleagues in pharmacology, medicinal chemistry, protein engineering, and computational and translational sciences to drive target identification/validation, drug discovery, and development
- Foster a culture of scientific excellence and innovation by staying abreast of scientific advances and emerging technologies in immunology and inflammation
Qualifications
- PhD, MS, BS (PhD preferred) in Immunology, Cellular and Molecular Biology, or a related scientific field with 0-2+ years of industry experience, preferably in inflammatory and autoimmune disease drug discovery (MS with 4+ years experience, BS with 6+ years experience)
- Strong expertise in immune cell biology (innate and adaptive immunity), cell signaling, and immunological assay development
- Hands-on experience with relevant techniques, including, biochemical and cellular assay development, tissue culture, multiparametric flow cytometry (e.g. 15+ colors), ELISA/MSD, RNA & protein analysis (e.g. RNA-seq/qPCR, Jess), CRISPR
- Isolation and culture of primary murine and human cells or patient-derived samples
- Experience with disease models of inflammation and/or autoimmunity is a plus
- Ability to work in a fast-paced, collaborative environment
- Strong problem-solving skills and ability to work independently and in team settings
Preferred Qualifications
- Prior experience in biotech/pharma drug discovery or translational research
- Experience working with small-molecule and biologics drug discovery
- Experience with multiomics analyses (e.g. genomic, transcriptomic, proteomics, etc.)
Requirements
- PhD, MS, BS (PhD preferred) in Immunology, Cellular and Molecular Biology, or a related scientific field
- 0-2+ years of industry experience, preferably in inflammatory and autoimmune disease drug discovery (MS with 4+ years experience, BS with 6+ years experience)
- Strong expertise in immune cell biology (innate and adaptive immunity), cell signaling, and immunological assay development
- Hands-on experience with biochemical and cellular assay development, tissue culture, multiparametric flow cytometry (e.g. 15+ colors), ELISA/MSD, RNA & protein analysis (e.g. RNA-seq/qPCR, Jess), CRISPR
- Isolation and culture of primary murine and human cells or patient-derived samples
- Ability to work in a fast-paced, collaborative environment
- Strong problem-solving skills and ability to work independently and in team settings
Benefits
- Medical, Dental & Vision
- Life Insurance
- Fitness & Wellness Programs
- Short-Term Disability
- Long-Term Disability
- Paid Vacation
- Paid Holidays
- Sick Time
- Paid Parental Leave
- 401(k) Matching
- Employee Stock Purchase Plan
- Tuition Reimbursement
- Employee Resource Groups
Company overview
Founded in 1978, Biogen is a leading global biotechnology company headquartered in Cambridge, Massachusetts, specializing in the development and commercialization of innovative therapies for serious neurological and neurodegenerative diseases. As one of the oldest independent biotechnology companies in the United States, Biogen has established itself as a pioneer in neuroscience, focusing on difficult-to-treat conditions where few or no treatment options exist. The company's portfolio includes groundbreaking treatments for multiple sclerosis, spinal muscular atrophy, Alzheimer's disease, ALS, and Friedreich's ataxia. With approximately 7,000 employees worldwide, Biogen operates through a global network that includes research and development hubs in Cambridge, Research Triangle Park in North Carolina, and South San Francisco, along with world-class manufacturing facilities in the United States and Switzerland. The company's commitment to scientific innovation is demonstrated by its Nobel Prize-winning founders and its receipt of the U.S. National Medal of Technology and Innovation. Biogen's patient-centric approach drives its mission to deliver transformative medicines that improve lives while creating sustainable value for shareholders and communities.