Scientist – Inflammation Research
Amgen
Summary
In this vital role you will perform in vitro and in vivo experiments—including determination of effects of drug targets using organoid and air liquid interface primary cell cultures and testing novel drug targets in mouse models of inflammatory disease.
Job description
What you will do
In this vital role you will perform in vitro and in vivo experiments—including determination of effects of drug targets using organoid and air liquid interface primary cell cultures and testing novel drug targets in mouse models of inflammatory disease.
This position will also involve analysis of lung epithelium function, repair, and regeneration. You will collaborate with a dynamic research team from multiple Amgen functional areas.
Key Responsibilities
- Perform both in vitro and in vivo experiments.
- Generate high-quality experimental data to support target identification, validation and progression of Inflammation research programs.
- Propose drug targets for respiratory diseases integrating human genetics, in vitro/in vivo studies, and published literature.
- Use AI-driven approaches to generate mechanistic insights, refine therapeutic hypotheses, and guide experimental design.
- Ability to balance scientific rigor with urgency and adaptability in a dynamic research environment.
- Publish and present at conferences.
Basic Qualifications
Doctorate degree OR Master’s degree and 2 years of Biological Sciences / Biomedical Sciences experience OR Bachelor’s degree and 4 years of Biological Sciences / Biomedical Sciences experience
Preferred Qualifications
- PhD with strong background and research experience in epithelial biology and inflammation.
- Experience performing both in vitro and in vivo experiments.
- Expertise in 2D and 3D primary cell cultures / co-cultures / human tissue cultures and mouse disease models.
- Technical expertise in mouse respiratory disease models and measurement of pulmonary mechanics.
- Strong publication record or significant contributions to therapeutic development programs.
Requirements
- Doctorate degree OR Master’s degree and 2 years of Biological Sciences / Biomedical Sciences experience OR Bachelor’s degree and 4 years of Biological Sciences / Biomedical Sciences experience
- PhD with strong background and research experience in epithelial biology and inflammation
- Experience performing both in vitro and in vivo experiments
- Expertise in 2D and 3D primary cell cultures / co-cultures / human tissue cultures and mouse disease models
- Technical expertise in mouse respiratory disease models and measurement of pulmonary mechanics
- Strong publication record or significant contributions to therapeutic development programs
Benefits
- Health insurance
- Dental coverage
- Vision coverage
- Life insurance
- Disability insurance
- Retirement and savings plan
- Flexible spending accounts
- Annual bonus program
- Stock-based long-term incentives
- Paid time-off
Company overview
Amgen Inc. is a leading American multinational biopharmaceutical company headquartered in Thousand Oaks, California, founded in 1980. As one of the world's largest independent biotechnology companies, Amgen specializes in discovering, developing, manufacturing, and delivering innovative human therapeutics. The company focuses on six key therapeutic areas: inflammation, oncology/hematology, bone health, cardiovascular disease, nephrology, and neuroscience. Amgen's portfolio includes blockbuster drugs such as Enbrel for autoimmune diseases, Prolia and XGEVA for osteoporosis, Repatha for cholesterol management, Otezla for psoriasis, and Neulasta for chemotherapy-induced neutropenia. With approximately 28,000 employees worldwide, Amgen operates as a component of both the Dow Jones Industrial Average and Nasdaq-100 indices. The company maintains a robust research and development pipeline with numerous clinical programs across various stages, leveraging cutting-edge biotechnology and human genetic data to address some of the world's most challenging diseases. Amgen's manufacturing capabilities span multiple global locations, and it distributes products through pharmaceutical wholesale distributors and direct-to-consumer channels.