Scientist, Large Molecule Analytical (On-site)
MSD
Summary
The Large Molecule Analytical department of our Research & Development Division is seeking applicants for a Scientist position. The Scientist is a laboratory-based scientific role tasked with solving complex analytical problems at the interface of biology, chemistry, and lab informatics disciplines to enable development of Biologics drug substances and drug products.
Job description
The successful candidate must function well and be able to collaborate in a fast-paced, integrated, multidisciplinary team environment. The qualified candidate will be responsible for development, qualification, implementation, troubleshooting and transfer of analytical methods for monoclonal proteins or other complex therapeutic proteins.
Applicants must have effective organizational, multi-tasking, oral/written communications skills, show scientific leadership, and a desire to conduct research and publish. Evidence of strong cross-functional collaboration in an academic or industrial setting is also preferred.
Qualifications
Education: BA/BS in analytical chemistry/biochemistry or related field with a minimum of 3 years of experience in the Pharmaceutical Industry, or M.S. with a minimum of 0+ year relevant experience (with expected graduation no later than January 2027).
Required Experience and Skills
- Prior experience in a laboratory environment
- Ability to develop and apply basic principles and scientific concepts to execute work in a laboratory setting
- Execute routine experiments and data interpretation with appropriate technical guidance
- Ability to operate and troubleshoot analytical methods
- Understanding of the fundamentals in separations science
- Experience with UPLC/HPLC analysis of biologics (e.g., SEC, RP, IEX) and CE techniques or molecular biology (PCR, DNA extraction) and immunoassay (ELISA, gel electrophoresis) techniques
- Ability to work within overall project timelines to manage prioritization and execution of individual deliverables with appropriate supervision
- Demonstrated experience working within collaborative team environments
- Experience in authoring and reviewing internal technical reports, sections of regulatory filings (e.g., IND, BLA) and external scientific publications
Preferred Experience and Skills
- Past experience working as part of a project team
- Strong knowledge of protein structure and degradation pathways
- Experience in analysis of various Biologic modalities (e.g., mAb, antibody-drug conjugate, fusion protein)
- Background in Analytical Methodologies and sound scientific understanding of Critical Quality Attributes/QbD/DOE principles
- Prior experience with Microsoft Office and other research applications (e.g., RLIMS, ELN, Empower)
- Experience in data analytics, programming, or laboratory automation
Requirements
- BA/BS in analytical chemistry/biochemistry or related field with a minimum of 3 years of experience in the Pharmaceutical Industry, or M.S. with a minimum of 0+ year relevant experience
- Prior experience in a laboratory environment
- Ability to develop and apply basic principles and scientific concepts to execute work in a laboratory setting
- Execute routine experiments and data interpretation with appropriate technical guidance
- Ability to operate and troubleshoot analytical methods
- Understanding of the fundamentals in separations science
- Experience with UPLC/HPLC analysis of biologics (e.g., SEC, RP, IEX) and CE techniques or molecular biology (PCR, DNA extraction) and immunoassay (ELISA, gel electrophoresis) techniques
- Ability to work within overall project timelines to manage prioritization and execution of individual deliverables with appropriate supervision
- Demonstrated experience working within collaborative team environments
- Experience in authoring and reviewing internal technical reports, sections of regulatory filings (e.g., IND, BLA) and external scientific publications
Benefits
- Medical Insurance
- Dental Insurance
- Vision Insurance
- Other Insurance Benefits
- 401(k)
- Paid Holidays
- Vacation
- Compassionate Leave
- Sick Leave
- Annual Bonus
- Long-Term Incentive
Company overview
MSD, known as Merck Sharp & Dohme outside the United States and Canada, is a global research-intensive biopharmaceutical company headquartered in Rahway, New Jersey. Founded in 1891, the company has established itself as one of the world's leading pharmaceutical corporations with a rich history spanning over 130 years. MSD operates as the international division of Merck & Co., Inc., focusing on the discovery, development, manufacturing, and marketing of innovative medicines, vaccines, biologic therapies, and animal health products. The company's extensive portfolio includes groundbreaking treatments in oncology, infectious diseases, cardiology, diabetes, and vaccines, with notable products such as Keytruda (pembrolizumab) for cancer immunotherapy, Gardasil for HPV prevention, and Januvia for diabetes management. MSD maintains a strong commitment to research and development, investing significantly in scientific innovation to address unmet medical needs worldwide. With approximately 75,000 employees globally, the company operates through four main segments: pharmaceuticals, animal health, healthcare services, and strategic alliances. MSD's mission centers on using leading-edge science to save and improve lives around the world, guided by the principle that medicine is for people, not profits.