Scientist, mRNA Formulation
GSK
Summary
Join GSK as a Scientist focused on mRNA formulation, where you will design and develop innovative mRNA delivery systems that support our vaccine and medicine discovery programs. Working closely with colleagues across disciplines, you will lead laboratory studies that enhance product understanding and accelerate development.
Job description
Responsibilities
- Design, prepare, and evaluate mRNA formulations and delivery systems, including lipid nanoparticle (LNP) platforms, to assess stability, compatibility, encapsulation efficiency, and performance.
- Develop and execute formulation studies, stability studies, and stress studies to advance mRNA vaccine and therapeutic programs.
- Characterize physicochemical properties of mRNA formulations using analytical techniques such as dynamic light scattering (DLS), zeta potential, chromatography, and thermal analysis.
- Analyze and interpret experimental data, identify formulation risks and opportunities, and recommend strategies to improve product quality, stability, and performance.
- Collaborate closely with analytical, process development, regulatory, and quality teams to support project goals and advance development programs.
- Maintain accurate laboratory records, prepare study reports, and communicate scientific findings through presentations and technical documentation.
- Maintain the drug product laboratory space in a safe, organized, and inspection-ready manner.
- Support troubleshooting and problem-solving efforts to address formulation challenges.
Basic Qualifications
- BS, MS, or PhD in Pharmaceutical Sciences, Pharmaceutics, Chemical Engineering, Chemistry, Biochemistry, Biomedical Engineering, or a related scientific discipline (BS and a minimum of 5 years of relevant experience, MS and a minimum of 3 years of relevant experience, or PhD and 0 years of relevant experience).
- A minimum of 1 year of hands-on laboratory experience developing and evaluating mRNA-LNP formulations or other nucleic acid delivery systems.
Preferred Qualifications
- Advanced degree (Master's or PhD) in a relevant discipline.
- Experience with vaccine formulation, protein biologics, nanoparticle delivery systems, or other advanced drug delivery technologies.
- Experience designing and executing formulation studies, stability studies, and other drug product development experiments.
- Practical knowledge of lipid nanoparticle formulation development and characterization.
- Knowledge of high-throughput formulation screening and stability study design.
- Familiarity with process development, scale-up considerations and manufacturing handoffs.
- Familiarity with characterization techniques used to evaluate formulation quality, such as dynamic light scattering, zeta potential measurement, or chromatography.
Requirements
- BS, MS, or PhD in Pharmaceutical Sciences, Pharmaceutics, Chemical Engineering, Chemistry, Biochemistry, Biomedical Engineering, or a related scientific discipline
- BS with a minimum of 5 years of relevant experience, MS with a minimum of 3 years, or PhD with 0 years
- A minimum of 1 year of hands-on laboratory experience developing and evaluating mRNA-LNP formulations or other nucleic acid delivery systems
Benefits
- Competitive salary
- Annual bonus
- Healthcare programs
- Wellbeing programs
- Pension plan membership
- Shares and savings programme
- Paid holidays
- Vacation
- Paid caregiver leave
- Paid parental leave
- Paid medical leave
Company overview
GSK plc (formerly GlaxoSmithKline) is a British multinational pharmaceutical and biotechnology company headquartered in London, England. Founded in 2000 through the merger of Glaxo Wellcome and SmithKline Beecham, GSK has grown to become one of the world's leading healthcare companies with operations in over 150 countries. The company specializes in researching, developing, and manufacturing prescription medicines, vaccines, and consumer healthcare products. GSK's therapeutic areas include respiratory diseases, HIV/AIDS, oncology, immunology, and infectious diseases. The company is particularly renowned for its vaccine portfolio and has been at the forefront of developing treatments for major global health challenges. With approximately 70,000 employees worldwide, GSK maintains a strong commitment to scientific innovation and has a significant presence in key markets including the United States, Europe, and emerging economies. The company's mission is to unite science, technology, and talent to get ahead of disease together, aiming to positively impact the health of 2.5 billion people by the end of the decade.