Scientist, Sequencing and Plate-Based Assays

Position Summary

Bristol Myers Squibb is seeking a motivated and detail-oriented (Senior) Scientist to join our Analytical Development team. In this role, you will develop new analytical methods for the characterization of RNA therapeutics, and support routine and non-routine analytical testing activities critical to the advancement of our in vivo non-viral drug discovery and development pipeline. The ideal candidate possesses hands-on laboratory experience, a strong scientific foundation, and a commitment to data quality and compliance.

Key Responsibilities

• Develop sequencing (both NGS and Sanger) and qPCR methods for RNA therapeutics
• Develop plate-based assays (e.g. ELISA, MSD)
• Explore new techniques and technologies to characterize RNA
• Analyze, interpret, and summarize experimental data with accuracy; prepare clear and concise lab reports and technical summaries
• Contribute to writing regulatory documents, method protocols and reports
• Train and mentor junior team members
• Execute and document laboratory experiments according to established SOPs, protocols, and Good Laboratory Practice (GLP) standards
• Maintain laboratory equipment including calibration, troubleshooting, and coordination with vendors for preventive maintenance
• Ensure compliance with all safety regulations, environmental health and safety (EHS) guidelines, and BMS corporate policies
• Contribute to cross-functional teams, collaborating with colleagues in research, process development, and formulations

Required Qualifications

• PhD in Biochemistry, Chemistry, Biology, Pharmaceutical Sciences, or a related scientific discipline.
• 3–8 years of hands-on laboratory experience, preferably with RNA and/or LNPs, including academic research, internships, or industry roles.
• Proficiency with NGS and Sanger sequencing (sample preparation, instrumentation and data analysis)
• Proficiency with plate-based assays (qPCR, digital PCR, ELISA and others).
• Demonstrated ability to work independently and manage multiple priorities in a fast-paced environment while maintaining accuracy and attention to detail.
• Demonstrated ability to analyze data and present results to the team and the larger research community.

Preferred Qualifications

• Experience in a pharmaceutical or biopharmaceutical industry setting.
• Familiarity with QbD principles, ICH guidelines, analytical method lifecycle, GxP principles, and regulatory submission requirements.
• Experience with LIMS (Laboratory Information Management Systems) is a plus.
• Experience with (bio)analytical method validation (e.g., per FDA or EMA guidelines).
• Working knowledge of statistical analysis tools (e.g., GraphPad Prism, JMP, or Excel-based analysis).
• Experience with RNA characterization techniques (e.g., RT-PCR, RNAseq, SEC, CE).