Senior Accounting Manager
BillionToOne
Summary
The Senior Accounting Manager will oversee the accounting operations of a newly public company in its first full year of SOX 404(b) compliance, including managing the month-end close process, owning the integrity of the general ledger, and serving as a named control owner within our SOX framework. Reporting to the Director of Accounting, this role leads a team of GL and AP accountants, acts as a primary day-to-day contact for our external auditors, and is accountable for the monthly management reporting package including flux analysis and cost-per-test economics.
Job description
Responsibilities
- Manage the month-end and quarter-end close on a dependency-gated calendar in FloQast, including the journal entry control log, reconciliation sign-offs, and close checklist completion.
- Own the accuracy and integrity of the general ledger in NetSuite, including review of recurring and non-standard journal entries, balance sheet reconciliations, and root-cause resolution of posting and configuration issues.
- Serve as a named owner and reviewer for financial reporting, GL, and close-cycle controls; maintain control narratives and supporting documentation; ensure IPE meets completeness and accuracy standards; remediate deficiencies.
- Act as a day-to-day point of contact for the Big 4 external auditor and consulting advisors, managing PBC requests, walkthrough support, sample pulls, and interim and year-end fieldwork.
- Own the monthly management reporting package: month-over-month flux analysis by functional area, cost-per-test analytics, and a management summary for the CFO and leadership team.
- Lead, mentor, and develop a team of GL and AP accountants spanning general ledger, fixed assets, accounts payable, and payroll.
- Operationalize technical accounting conclusions in areas including ASC 842 lease accounting, ASC 730 R&D cost treatment, and self-funded health plan IBNR reserves.
- Drive improvements to the close and accounting processes bringing increased speed, efficiency, and operational compliance.
- Provide senior oversight of the vendor master and disbursement control environment, partnering with the Supply Chain team on procurement governance across the AP and payment cycle.
Qualifications
- 8-10+ years of progressive accounting experience, including 3+ years managing the close and leading a team of direct reports; post-IPO experience strongly preferred.
- Experience in life sciences, diagnostics, or another high-growth regulated industry is a plus.
- CPA required with deep US GAAP fluency.
- Big 4 or national audit firm experience is a plus.
- Hands-on SOX 404(b) experience as a control owner including familiarity with control narratives, IPE requirements, and deficiency remediation.
- Strong NetSuite experience required, with the ability to query the system directly (saved searches, and ideally SuiteQL); FloQast, Expensify, and Workiva experience are pluses.
- Advanced Excel and analytical abilities.
- Excellent communication and interpersonal skills, with the ability to collaborate effectively across departments.
- Bachelor's degree in Accounting, Finance, or a related field.
Requirements
- 8-10+ years of progressive accounting experience
- 3+ years managing the close and leading a team of direct reports
- CPA required
- Deep US GAAP fluency
- Hands-on SOX 404(b) experience as a control owner
- Familiarity with control narratives, IPE requirements, and deficiency remediation
- Strong NetSuite experience required
- Ability to query NetSuite directly (saved searches, ideally SuiteQL)
- Advanced Excel and analytical abilities
- Excellent communication and interpersonal skills
- Bachelor's degree in Accounting, Finance, or a related field
- Post-IPO experience strongly preferred
- Life sciences, diagnostics, or high-growth regulated industry experience a plus
- Big 4 or national audit firm experience a plus
- FloQast, Expensify, and Workiva experience a plus
Benefits
- Medical, Dental & Vision
- 401(k) Matching
- Paid Parental Leave
- Fertility Benefits
- Paid Time Off
- Equity Grants
- On-site Gym
- On-site Restaurant
- Free Daily Lunches
- EV Charging
Company overview
BillionToOne is a precision diagnostics company headquartered in Menlo Park, California, founded in 2016 with a mission to make molecular diagnostics more accurate, efficient, and accessible. The company has developed a proprietary Quantitative Counting Templates (QCT) molecular counting platform that can accurately count DNA molecules at the single-molecule level, enabling unprecedented sensitivity in disease detection. BillionToOne operates as a publicly traded company on NASDAQ under the symbol BLLN, having completed a successful IPO in 2025. The company's diagnostic platforms include UNITY Complete for non-invasive prenatal testing, which assesses fetal risk for recessive conditions and aneuploidies from a single maternal blood sample, and Northstar oncology products for cancer therapy selection and treatment response monitoring. With over 500 employees and multiple CLIA/CAP accredited laboratories, BillionToOne represents a significant advancement in quantitative molecular diagnostics, combining breakthrough science with scalable commercial operations to transform healthcare delivery.