Senior AI Engineer- Imaging
Roche
Summary
As an imaging-focused machine learning engineer within the AI Enablement team, you will work closely with computational scientists, biologists, bench scientists, AI/ML experts, product leaders, and software engineers. Your work will bridge scientific intuition with quantitative analysis, enable richer phenotypic analysis, and provide new multimodal capabilities across large-scale, state-of-the-art datasets. You will build, own, and constantly improve scalable AI/ML and computer vision systems that unlock the potential of diverse scientific imaging data (e.g., microscopy, digital pathology, biomedical imaging).
Job description
The Opportunity
- Design, develop, and test robust, scalable, and maintainable AI/ML scientific web applications and backend pipelines for high-throughput scientific imaging data processing and visualization.
- Build, evaluate, and fine-tune state-of-the-art computer vision and deep learning models (e.g., cell segmentation, cell classification, phenotypic profiling, tissue segmentation, feature extraction, image registration) applied to biological and clinical imaging modalities.
- Build tools to evaluate AI/ML and vision model performance, establish benchmark datasets, and quantify model quality, robustness, and drift over time.
- Partner with product managers, bioimage analysts, and research scientists to understand user workflows, shape requirements, and translate complex scientific imaging needs into actionable technical specifications.
- Develop and maintain scalable cloud infrastructures and data pipelines for collecting, structuring, storing, and accessing large-scale multi-dimensional imaging datasets (e.g., OME-TIFF, Zarr, HDF5).
- Optimize GPU memory footprint, batching, and inference throughput for large image pipelines and deep neural network models.
- Contribute to architectural decisions, code reviews, and the evolution of engineering and MLOps processes for computer vision models.
- Be willing to span the full stack and contribute where needed, even outside of core areas of expertise.
- Stay up-to-date with emerging computer vision technologies and industry best practices while promoting a culture of continuous learning, collaboration, and curiosity.
Who You Are
- PhD, Master's with 3-5 years, or Bachelor's with 4-7 years experience with a degree in Computer Science, Biomedical Engineering, Electrical Engineering, Computational Biology, or a related technical field with focus on machine learning engineering and computer vision.
- Strong proficiency with AI/ML frameworks and computer vision libraries (e.g., PyTorch, TensorFlow, OpenCV, MONAI, Scikit-Image, torchvision, Napari, or Bio-Formats).
- Deep expertise in computer vision algorithms (e.g., CNNs, Vision Transformers, UNet, SAM/Segment Anything, Cellpose).
- Expert knowledge of machine learning theory, image processing fundamentals, object detection, instance segmentation, and quantitative image analysis.
- Demonstrated experience working with high-dimensional scientific imaging data (e.g., fluorescence/brightfield microscopy, digital pathology whole slide images, high-content screening, multiplexed imaging).
- Strong knowledge of GPU acceleration, parallel computing, CUDA, and ML performance optimization for large image datasets.
- Experience with Kubernetes, relational databases, NoSQL databases, object storage, and cloud-native architectures in public clouds (ideally AWS).
- Proven understanding and application of software engineering best practices, CI/CD, and MLOps principles.
- Excellent communication skills and ability to build trusted partnerships with scientific collaborators, bioimage analysts, and cross-functional teams.
- Ability to quickly acquire new technologies, domain knowledge, and programming languages with a passion for continuous learning.
Preferred Qualifications
- Experience with multi-modal data fusion (combining scientific imaging with genomics, transcriptomics, or clinical tabular data).
- Experience working directly with biomedical scientists or in a pharma/biotech research environment.
- Experience with workflow automation, GenAI, Vision-Language Models, and/or AI agents.
Requirements
- PhD, Master's with 3-5 years, or Bachelor's with 4-7 years experience in Computer Science, Biomedical Engineering, Electrical Engineering, Computational Biology, or related technical field
- Strong proficiency with AI/ML frameworks and computer vision libraries (PyTorch, TensorFlow, OpenCV, MONAI, Scikit-Image, torchvision, Napari, Bio-Formats)
- Deep expertise in computer vision algorithms (CNNs, Vision Transformers, UNet, SAM/Segment Anything, Cellpose)
- Expert knowledge of machine learning theory, image processing fundamentals, object detection, instance segmentation, quantitative image analysis
- Demonstrated experience with high-dimensional scientific imaging data (microscopy, digital pathology, high-content screening, multiplexed imaging)
- Strong knowledge of GPU acceleration, parallel computing, CUDA, and ML performance optimization
- Experience with Kubernetes, relational databases, NoSQL databases, object storage, and cloud-native architectures in public clouds (ideally AWS)
- Proven understanding of software engineering best practices, CI/CD, and MLOps principles
- Excellent communication skills and ability to build trusted partnerships
- Ability to quickly acquire new technologies, domain knowledge, and programming languages
Benefits
- Discretionary annual bonus
- Medical, Dental & Vision
- 401(k) Matching
Company overview
Roche is a Swiss multinational healthcare company and a global pioneer in pharmaceuticals and diagnostics, founded in 1896 and headquartered in Basel, Switzerland. As the world's largest biotech company and the fifth-largest pharmaceutical company by revenue, Roche operates through two primary divisions: Pharmaceuticals and Diagnostics. The company is renowned for its leadership in personalized healthcare, combining strengths in both drug development and diagnostic testing to deliver tailored treatments for patients. Roche maintains a strong focus on oncology, immunology, infectious diseases, ophthalmology, and central nervous system disorders, with a portfolio that includes over 30 medicines on the World Health Organization's Model Lists of Essential Medicines. The company owns significant subsidiaries including Genentech, Chugai Pharmaceuticals, Ventana Medical Systems, and Foundation Medicine. With approximately 103,000 employees worldwide and operations in over 100 countries, Roche has established itself as a leader in cancer treatments globally while maintaining a robust pipeline of innovative therapies and diagnostic solutions. The company's commitment to sustainability has been recognized through ten consecutive years as Group Leader in the Dow Jones Sustainability Indices within the Pharmaceuticals, Biotechnology & Life Sciences Industry.