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Senior Data Scientist, Gen AI Application

Genentech

South San Francisco, CAHybridPosted 37 days ago$177,310 - $329,290/year
Full TimeSenior LevelTech & Data (Health IT)Biotechnology
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Summary

As a Sr. Data Scientist - Generative AI Applications within Genentech's Data, Digital, and Analytics (DDA) organization, you will bridge the gap between core AI infrastructure and high-impact business applications across Commercial, Medical, and Government Affairs (CMG). In this high-visibility role, you will design, build, and optimize intelligent agents and agentic workflows that reason, utilize complex tools, and automate intricate multi-step business processes. You will collaborate closely with platform engineers and business product owners to deliver seamless, reliable, and user-centric GenAI solutions that drive measurable business impact.

Job description

The Opportunity

As a Sr. Data Scientist - Generative AI Applications within Genentech's Data, Digital, and Analytics (DDA) organization, you will bridge the gap between core AI infrastructure and high-impact business applications across Commercial, Medical, and Government Affairs (CMG). In this high-visibility role, you will design, build, and optimize intelligent agents and agentic workflows that reason, utilize complex tools, and automate intricate multi-step business processes. You will collaborate closely with platform engineers and business product owners to deliver seamless, reliable, and user-centric GenAI solutions that drive measurable business impact.

  • Architect, build, and deploy intelligent AI agents, orchestration workflows, decision logic, and collaboration patterns for complex enterprise applications.
  • Define and implement robust tool schemas, APIs, permissions, error-handling mechanisms, and human-in-the-loop escalation paths for agentic systems.
  • Optimize agent behavior across key metrics including accuracy, task completion reliability, latency, cost efficiency, and end-user experience.
  • Design effective memory, context retention, retrieval-augmented generation (RAG), and summarization strategies to enhance agent capabilities.
  • Establish comprehensive evaluation frameworks, observability metrics, synthetic test scenarios, and trace analyses to diagnose failure modes and prevent hallucinations.
  • Partner with application engineers, platform teams, and business product managers to integrate agentic systems into secure, production-grade enterprise environments.
  • Standardize agent development patterns, guardrails, and best practices across the DDA organization.

Who you are

  • 5+ years of professional experience in software engineering, machine learning, or GenAI application development.
  • Hands-on experience designing, building, and deploying LLM-powered agents or agentic workflows in production environments.
  • Strong working knowledge of prompting techniques, tool calling, structured outputs, planning mechanisms, RAG, and context management.
  • Proficiency in Python, TypeScript, or a comparable production language, alongside experience with agent orchestration frameworks (e.g., LangGraph, LangChain, or custom frameworks).
  • Demonstrated expertise designing APIs, tool contracts, asynchronous workflows, and integration patterns for scalable systems.

Preferred

  • Experience with multi-agent architecture systems and inter-agent communication protocols (e.g., A2A, MCP).
  • Experience building and deploying agentic workflows within enterprise platforms or regulated industries (biotech, pharma, finance, or healthcare).
  • Familiarity with model routing, prompt versioning, fine-tuning, guardrails, and human-in-the-loop workflows.
  • Strong understanding of cloud environments (AWS, AWS AgentCore), identity, access management, data privacy, and secure tool execution.
  • Proven track record translating ambiguous business objectives into reliable technical agent workflows and quantifiable outcomes.

Location

This role is based in South San Francisco and offers a hybrid schedule working 3 days per week on campus. No relocation benefits are available for this posting.

Requirements

  • 5+ years of professional experience in software engineering, machine learning, or GenAI application development
  • Hands-on experience designing, building, and deploying LLM-powered agents or agentic workflows in production environments
  • Strong working knowledge of prompting techniques, tool calling, structured outputs, planning mechanisms, RAG, and context management
  • Proficiency in Python, TypeScript, or a comparable production language
  • Experience with agent orchestration frameworks (e.g., LangGraph, LangChain, or custom frameworks)
  • Demonstrated expertise designing APIs, tool contracts, asynchronous workflows, and integration patterns for scalable systems

Benefits

  • Hybrid schedule (3 days on campus)
  • Discretionary annual bonus
  • No relocation benefits

Company overview

Genentech, founded in 1976 and now a member of the Roche Group, is widely recognized as the pioneer of the biotechnology industry. The company has been at the forefront of scientific innovation for nearly 50 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech's transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. With over 10,000 employees, the company operates from its South San Francisco headquarters and maintains a strong focus on oncology, immunology, neuroscience, ophthalmology, and infectious diseases. Genentech continues to pursue groundbreaking science while maintaining its startup spirit within the Roche organization, consistently delivering on its promise to improve patients' lives through innovative biopharmaceutical solutions.

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