Senior Director, Applied AI Solutions- Clinical Drug Development

Key Responsibilities

• Applied AI engineering roadmap: translate prioritized AI demand into a multi-year applied AI engineering and delivery plan tied to CDS and Development outcomes.
• AI solution design and delivery (0→1): own the design, build, evaluation, and technical validation of AI services, applications, agents, and shared components through first production release.
• Agentic systems and interoperability: guide responsible use of agentic patterns for bounded, auditable CDS workflows using open interoperability protocols such as MCP and A2A.
• AI engineering excellence: define and uphold ARC's applied AI engineering practices — data contracts, model and prompt lifecycle management, evaluation harnesses, LLMOps/MLOps, automated testing, and reproducible releases.
• Evaluation, observability, and responsible AI: establish offline and online evals, gold-standard datasets, task and outcome metrics, trace-based observability, model and data monitoring, adversarial testing, and incident response.
• Adoption and value realization: co-own product discovery and experience design with PMx and support adoption alongside CDS workflow owners.
• Team and technical leadership: build, lead, and develop a high-performing team spanning applied AI, machine learning, and software and data engineering.
• Ecosystem stewardship: contribute the AI assessment that informs build, buy, and partner decisions taken jointly with business owners and IT; manage strategic AI vendors.

Required Qualifications

• Bachelor's degree with 14+ years of relevant experience, Master's degree with 13+ years, or PhD with 12+ years in computer science, engineering, data science, computational science, bioinformatics, or a related quantitative field.
• Meaningful, current hands-on experience personally developing and maintaining AI systems and applications.
• Substantial experience leading applied AI, ML, or data engineering organizations while remaining technically hands-on.
• Demonstrated delivery of AI products or reusable capabilities from problem framing through validated release, adoption, and value measurement.
• Deep working knowledge of modern AI system design, including foundation models and LLMs, RAG and semantic retrieval, agent and tool orchestration, model selection and routing, structured outputs, evaluation, guardrails, and human-in-the-loop patterns.
• Strong software and platform engineering judgment across APIs, distributed systems, cloud services, data design, security, CI/CD, MLOps/LLMOps, observability, and production reliability.
• Experience implementing AI in environments with rigorous privacy, security, quality, compliance, validation, or regulatory expectations.
• Track record of hiring, developing, and retaining multidisciplinary technical teams and coaching senior engineers and technical leaders.
• Executive-level communication and influence.

Preferred Qualifications

• Experience in pharmaceutical, biotechnology, healthcare, or another regulated scientific domain, with familiarity across clinical development data and workflows.
• Experience applying AI to clinical data review, study design or operations, safety, biomarkers, real-world evidence, regulatory evidence, or scientific knowledge workflows.
• Practical experience designing or governing MCP servers and clients, A2A-enabled systems, or comparable open, vendor-neutral interoperability patterns.
• Experience with multimodal biomedical data, ontologies, knowledge graphs, privacy-preserving methods, causal inference, or statistical and ML methods used in clinical research.
• Evidence of external technical leadership through open-source contributions, patents, peer-reviewed work, conference presentations, standards participation, or substantive industry collaborations.