Senior Director, Clinical Science, Vaccines, Hybrid

Role Overview

The Senior Director, Clinical Science, Vaccines provides strategic Clinical Science leadership across multiple studies, programs, and assets, contributing to disease area strategy and promoting consistency in scientific standards, medical data review practices, and decision-making across the portfolio.

Key Responsibilities

• Provide strategic Clinical Science leadership across the disease area, including multiple studies, programs, and assets.
• Contribute to disease area strategy with Clinical Science input on development opportunities, scientific considerations, portfolio risks, and emerging data.
• Apply expert knowledge of therapeutic focus, disease biology, treatment landscape, and clinically meaningful endpoints to inform study planning, data interpretation, and issue resolution.
• Lead efforts to standardize Clinical Science approaches, including medical data review practices, data interpretation principles, and key deliverables.
• Guide interpretation of clinical data across studies, cohorts, and assets to support understanding of trends, opportunities, risks, and program implications.
• Contribute scientific perspective to protocol development, amendments, study design, endpoint selection, eligibility criteria, and biomarker strategy discussions.
• Contribute Clinical Science perspective to portfolio discussions, governance reviews, and senior leadership meetings.
• Provide direct management for Directors, Principal Scientists, and Clinical Scientists, setting expectations and supporting talent development.
• Partner closely with Clinical Operations, Regulatory Affairs, Biostatistics, Data Management, Drug Safety and Pharmacovigilance, Translational Medicine, and Medical Affairs.
• Ensure Clinical Science activities comply with regulatory requirements, company policies, and established procedures; support inspection readiness.

Qualifications, Skills & Experience

• Advanced scientific or healthcare degree required (e.g., PhD, PharmD), or equivalent, and 8+ years of pharmaceutical, clinical drug development, and/or medical field experience preferred.
• OR Master's degree, preferably in life sciences, and 12+ years of pharmaceutical, clinical drug development, and/or medical field experience.
• OR Bachelor's degree, preferably in life sciences, and 15+ years of pharmaceutical, clinical drug development, and/or medical field experience.
• Significant experience in Clinical Development, Clinical Science, clinical drug development, or a related function within the pharmaceutical or biotechnology industry.
• Demonstrated experience providing Clinical Science leadership across multiple studies, programs, or assets.
• Deep therapeutic area expertise, including disease biology, treatment landscape, clinically relevant endpoints, and scientific considerations affecting development.
• Strong understanding of clinical trial design, clinical development strategy, clinical data review, and interpretation of oncology data.
• Experience contributing to disease area strategy, portfolio discussions, or cross-program planning.
• Experience contributing to regulatory submissions, safety reviews, or health authority interactions.
• Experience working effectively in cross-functional teams within a matrix environment.
• Demonstrated ability to integrate information across studies and programs to support scientific and business decisions.
• Excellent communication, influence, and executive presentation skills.
• Demonstrated people leadership experience, including management, coaching, and development of scientific staff.