
Senior Director, Digital Forensics & Incident Response
AstraZeneca
Summary
The Senior Director, Digital Forensics & Incident Response owns AstraZeneca's global capability to respond to and investigate cyber incidents. This role commands the enterprise response to material incidents across cloud, on-premises and OT/ICS environments; owns incident governance, readiness and the forensic defensibility of all collected evidence; and is accountable for executive reporting, lessons learned and the control hardening that follows. This is a build role as AstraZeneca matures its internal incident response capability.
Job description
About the Role
The Senior Director, Digital Forensics & Incident Response owns AstraZeneca's global capability to respond to and investigate cyber incidents. This role commands the enterprise response to material incidents across cloud, on-premises and OT/ICS environments; owns incident governance, readiness and the forensic defensibility of all collected evidence; and is accountable for executive reporting, lessons learned and the control hardening that follows. This is a build role as AstraZeneca matures its internal incident response capability.
What You'll Do
- Incident Command: Act as the accountable commander for material and crisis-level cyber incidents, driving scoping, containment, eradication, recovery and investigation across hybrid cloud, on-premises and OT/ICS environments.
- Service Line Ownership: Own the Incident Response strategy, multi-year roadmap, operating budget and capability plan.
- Incident Governance: Define and maintain incident categories, severity definitions, activation criteria, decision authorities, delegation of authority during out-of-hours events and the handoff into enterprise crisis management.
- Forensic Defensibility: Ensure that evidence is preserved, collected and analysed with chain-of-custody rigor that stands up to legal and regulatory scrutiny. Own the relationship with Legal regarding litigation hold, privilege and retention.
- Readiness and Exercises: Run a calendar of tabletop, functional and purple-team exercises reaching from analyst level to the Executive Committee.
- Coverage Model: Guarantee 24x7 response coverage with credible follow-the-sun handoffs, issue paths and surge capacity.
- Automation and AI: Operationalise agentic SIEM capability, XDR and SOAR playbooks, LLM-assisted runbooks and automated triage packages.
- Metrics and Reporting: Own Incident Response targets and key risk indicators, including mean time to detect, contain and respond, dwell time, containment quality and business impact.
- Executive and Board Communication: Deliver incident briefings, written updates and quarterly lessons-learned reviews to the CISO and IT leadership and, where warranted, the Audit Committee.
- Regulatory and Notification Support: Work with Legal, Privacy and Compliance to support breach-notification assessments and regulatory obligations.
- Controls Hardening: Drive post-incident detection and control improvements with Detection Engineering, Identity, Cloud, Endpoint, Network and OT teams.
- Build and Organization Design: Design and staff the DFIR function from a near-zero baseline, defining roles, levels, sourcing locations and the balance of permanent and retained capacity.
- Leading Through Leaders: Manage a Director-level leader and incident managers; set objectives, review performance and develop successors.
- Talent and Capability: Lead inclusive recruitment and build genuine career paths and upskilling in DFIR, cloud and identity forensics, OT/ICS, malware analysis and automation.
- Budget and Commercial Management: Own the service line budget, tooling and retainer spend, and build the case for further investment.
Knowledge, Experience and Understanding
- Incident Command and the Incident Response Lifecycle: Proven command across the full lifecycle at enterprise scale.
- Digital Forensics and Evidence Handling: Experience managing the collection, preservation and analysis of digital evidence; chain of custody; timeline reconstruction; attribution; and concise executive reporting of forensic findings.
- Attacker Tradecraft: Deep working knowledge of the attack lifecycle and MITRE ATT&CK, common threat actor tactics, techniques and procedures.
- Automation and AI in Operations: Experience operationalising modern security tooling, including SIEM, SOAR and XDR, together with artificial intelligence, large language model and agentic capabilities.
- Cloud, Identity and Endpoint Visibility: Understanding of telemetry and logging priorities across major cloud platforms, identity providers, operating systems and security tooling.
- Operational Technology: Experience coordinating response in manufacturing OT/ICS environments.
- Regulated-Industry Constraints: Experience working within GxP and validated-system requirements, clinical and patient data sensitivities and third-party exposure considerations.
- Legal, Regulatory and Crisis Communications: Ability to build durable partnerships with Legal, Privacy, Risk and Compliance, Communications and Physical Security.
- Vendor and Retainer Readiness: Experience maintaining retainer partner readiness and integrating external specialists during major incidents.
Minimum Skills and Experience Required
- Education: Bachelor's degree
- Number of Years of Experience: 10+ years of experience
- Professional Experience: Demonstrated experience in cybersecurity, including incident response or digital forensics.
- Leadership Experience: Demonstrated experience leading incident response in a large, complex enterprise, including managing other people leaders or managers.
- Command Experience: Demonstrable record as the accountable commander for high-severity incidents spanning hybrid cloud, on-premises and OT environments.
- Global Coordination: Experience running or integrating distributed 24x7 teams across multiple regions and cultures, including follow-the-sun handoffs.
- Communication and Facilitation: Ability to explain complex technical situations in clear business terms, produce concise written material under time pressure and lead briefings for senior executives.
- Analytical Decision-Making: Ability to assess incomplete information, weigh risk and balance strategic and tactical demands against business pragmatism and risk appetite.
- Cross-Functional Credibility: Demonstrated ability to collaborate across IT, Legal, GRC and Physical Security.
- Availability: Willingness to serve as the senior escalation point outside business hours and to travel internationally as incidents and readiness activities require.
Desirable Skills and Experience
- Education: Bachelor's Degree in information security, computer science or a related field, or equivalent practical experience.
- Certifications: CISSP, CISM, GIAC certifications such as GCIH, GCFA, GREM or GNFA, and CCSP.
- Sector Experience: Experience in pharmaceutical, life sciences, healthcare or another highly regulated industry with significant manufacturing OT exposure.
- Board and Regulator Exposure: Experience briefing an audit committee or board, or engaging directly with regulators or law enforcement during a significant incident.
- Commercial Experience: Experience negotiating and governing Incident Response retainers and forensic vendor arrangements across multiple jurisdictions.
- Language Skills: Working proficiency in a second language relevant to AstraZeneca's delivery hubs.
Requirements
- Bachelor's degree
- 10+ years of experience in cybersecurity, including incident response or digital forensics
- Demonstrated experience leading incident response in a large, complex enterprise, including managing other people leaders or managers
- Demonstrable record as the accountable commander for high-severity incidents spanning hybrid cloud, on-premises and OT environments
- Experience running or integrating distributed 24x7 teams across multiple regions and cultures, including follow-the-sun handoffs
- Ability to explain complex technical situations in clear business terms and lead briefings for senior executives
- Ability to assess incomplete information, weigh risk and balance strategic and tactical demands
- Demonstrated ability to collaborate across IT, Legal, GRC and Physical Security
- Willingness to serve as the senior escalation point outside business hours and to travel internationally
- Experience managing the collection, preservation and analysis of digital evidence; chain of custody; timeline reconstruction; attribution
- Deep working knowledge of the attack lifecycle and MITRE ATT&CK
- Experience operationalising SIEM, SOAR and XDR, together with AI, LLM and agentic capabilities
- Understanding of telemetry and logging priorities across major cloud platforms, identity providers, operating systems and security tooling
- Experience coordinating response in manufacturing OT/ICS environments
- Experience working within GxP and validated-system requirements
- Experience maintaining retainer partner readiness and integrating external specialists during major incidents
Benefits
- 401(k) Matching
- Paid Vacation
- Paid Holidays
- Paid Leaves
- Medical, Dental & Vision
- Prescription Drug Coverage
- Short-Term Incentive Bonus
- Equity-Based Long-Term Incentive
- Overtime Pay
Company overview
AstraZeneca is a global, science-led, patient-focused pharmaceutical company dedicated to accelerating the delivery of life-changing medicines that create enduring value for patients, society, and shareholders. With a workforce of over 94,300 employees worldwide, the company operates across three core therapy areas: Oncology, BioPharmaceuticals (including Cardiovascular, Renal & Metabolism, Respiratory & Immunology), and Rare Disease. Headquartered in Cambridge, UK, AstraZeneca maintains strategic R&D centers in Cambridge, Gaithersburg (US), Boston (US), Gothenburg (Sweden), Shanghai, and Beijing. The company generated $54.1 billion in total revenue in 2024 and invested $13.6 billion in scientific research and development. AstraZeneca's bold aspiration is to be pioneers in science, lead in disease areas, and transform patient outcomes, with a goal to launch 20 new medicines and achieve $80 billion in total revenue by 2030. The company is recognized for its commitment to sustainability, health equity, and creating an inclusive work environment where diverse perspectives drive innovation.