AstraZeneca logo

Senior Director Global Oral Solid Dosage Forms (Global OSD), Technical Operations, Science & Innovation

AstraZeneca

Mount Vernon, INHybridPosted 24 days ago$209,559.20 - $314,338.80/year
Full TimeDirector & AboveManufacturing & CMCPharmaceutical
Original posting ↗

Summary

This senior leadership role provides strategic and operational direction for the global organisation responsible for on-market technical support to AstraZeneca's commercial Oral Solid Dosage (OSD) portfolio. Based in Newark, US, with frequent office presence in Mt. Vernon. The position leads a high-performing team that supports OSD platform teams and senior scientific experts, ensuring robust, reliable and innovative manufacturing performance across the product lifecycle.

Job description

Accountabilities

In this role, the Senior Director Global OSD leads and develops a diverse technical organisation focused on delivering strong product and process performance for AstraZeneca's commercial OSD portfolio. The position manages and coaches direct reports, building capability, engagement and succession while fostering a culture of continuous improvement and innovation. As a key member of the North Americas Commercial Operations Leadership Team, the role shapes regional strategy, aligns cross-functional priorities and translates strategy into clear, actionable plans that drive value across the network.

The Senior Director is accountable for proactively managing product and process robustness, using data, AI and advanced analytics to generate insights and drive performance improvements. The role develops and implements science and innovation strategies for OSD manufacturing, with particular emphasis on material science, pharmaceutics and new technology introduction in partnership with Manufacturing Technology and Product Development. A critical part of the remit is to maintain a best-in-class technical support model for internal manufacturing sites and external partners, ensuring outstanding customer service and effective risk management.

The Senior Director sets clear direction, communicates with impact and influences at all levels to embed Lean principles, operational excellence and compliant ways of working across the function. The role also carries financial accountability for the team's budget, including headcount and revenue, ensuring resources are deployed effectively to deliver strategic priorities. Operating confidently in a global environment, the Senior Director builds an organisation ready for future challenges and change, contributing significantly to the success of Operations and the commercial viability and availability of current products.

Essential Skills/Experience

  • Have an excellent understanding of the overall drug development and commercialization process from development, launch and through life cycle management
  • Extensive pharmaceutical proven experience specifically in relation to Oral Solid Dosage (OSD) form drug products.
  • Have a broad understanding of the various scientific subject areas that they have accountability for with expert knowledge of Oral Solid Dosage form manufacturing technology.
  • Have a detailed understanding of principles, applications and management of SHE, cGMP and Lean.
  • Experience in Operations and/or R&D with a track record of successful project leadership and delivery within a matrix organization and lean leadership.
  • Evidence of excellent communication skills and build excellent relationships with customers/key partners.
  • Proven experience leading large, multi-site or global technical organisations within commercial manufacturing
  • Extensive experience in the application and industrialisation of innovative manufacturing technologies, with preference for expertise in continuous manufacturing platforms, particularly Continuous Direct Compression (CDC)
  • Demonstrated success in deploying AI, digital or sophisticated analytics solutions to improve manufacturing performance
  • Successful leadership of new technology introduction across pharmaceutical development and commercial manufacturing networks
  • Strong background in material science or pharmaceutics applied to OSD development or commercialisation
  • Experience introducing new technologies or platform capabilities into commercial operations at scale
  • Track record of building high-performing, inclusive teams and developing senior technical leaders
  • Demonstrable experience overseeing substantial budgets and leading investment decisions within a complex operational environment.
  • An understanding of capital planning and the budgeting lifecycle—encompassing forecasting, prioritisation, approval governance, and performance tracking—would be highly advantageous.

Requirements

  • Excellent understanding of drug development and commercialization process
  • Extensive pharmaceutical experience in Oral Solid Dosage (OSD) form drug products
  • Expert knowledge of Oral Solid Dosage form manufacturing technology
  • Detailed understanding of SHE, cGMP and Lean principles
  • Experience in Operations and/or R&D with project leadership in matrix organization
  • Excellent communication skills and relationship building
  • Proven experience leading large, multi-site or global technical organisations
  • Experience in industrialisation of innovative manufacturing technologies
  • Preference for expertise in continuous manufacturing platforms, particularly Continuous Direct Compression (CDC)
  • Demonstrated success in deploying AI, digital or analytics solutions
  • Leadership of new technology introduction across development and commercial manufacturing
  • Strong background in material science or pharmaceutics applied to OSD
  • Experience introducing new technologies into commercial operations at scale
  • Track record of building high-performing, inclusive teams
  • Experience overseeing substantial budgets and leading investment decisions
  • Understanding of capital planning and budgeting lifecycle

Benefits

  • 401(k) plan
  • Paid vacation
  • Paid holidays
  • Paid leaves
  • Medical insurance
  • Prescription drug coverage
  • Dental insurance
  • Vision coverage
  • Short-term incentive bonus
  • Equity-based long-term incentive

Company overview

AstraZeneca is a global, science-led, patient-focused pharmaceutical company dedicated to accelerating the delivery of life-changing medicines that create enduring value for patients, society, and shareholders. With a workforce of over 94,300 employees worldwide, the company operates across three core therapy areas: Oncology, BioPharmaceuticals (including Cardiovascular, Renal & Metabolism, Respiratory & Immunology), and Rare Disease. Headquartered in Cambridge, UK, AstraZeneca maintains strategic R&D centers in Cambridge, Gaithersburg (US), Boston (US), Gothenburg (Sweden), Shanghai, and Beijing. The company generated $54.1 billion in total revenue in 2024 and invested $13.6 billion in scientific research and development. AstraZeneca's bold aspiration is to be pioneers in science, lead in disease areas, and transform patient outcomes, with a goal to launch 20 new medicines and achieve $80 billion in total revenue by 2030. The company is recognized for its commitment to sustainability, health equity, and creating an inclusive work environment where diverse perspectives drive innovation.

Explore more jobs of your matchFind more biopharma roles with GetBioJob.