Senior Director, Medical Affairs

Decoding The Role

The primary focus of this role is to lead medical and scientific strategic planning and operational execution of core medical affairs activities from early-clinical phase through lifecycle management for our lead in vivo development candidate, EDIT-401, a potential best-in-class, one-time therapy designed to significantly reduce LDL cholesterol levels. This role will build Medical Affairs capabilities while providing scientific leadership and strategic direction across cross-functional teams and strong engagement with external stakeholders.

As the Senior Director, Medical Affairs you will:

• Develop and lead Medical Affairs strategies including medical communications, engagement with opinion leaders, data dissemination, and external collaborations
• Establish and execute a strategic publication and congress plan; work with internal colleagues to develop key messages on unmet need, mechanism of action, and target product profile
• Build core scientific platforms, disease-state education materials, and standard medical response documents working closely with Clinical Development, Regulatory, Research, and Legal to develop a consistent, compliant scientific narrative
• Serve as internal medical-scientific expert, providing scientific interpretation of data (clinical trials, real-world evidence, published literature) and translating insights into actionable medical strategy
• Cultivate and maintain trusted relationships with the medical community by driving scientific exchange with thought leaders, investigators, steering committees, and medical societies.
• Design and lead scientific advisory boards to gather insights on clinical trial designs, patient selection criteria, target product profile and lifecycle planning
• Partner with Clinical Operations and Clinical Development to provide input in design and execution of clinical trial programs and facilitate enrollment of company sponsored clinical trials
• Engage with patient advocacy organizations to build trust and awareness within the community
• Direct external medical communication agencies, manage operational budgets, and mentor internal team members

The Ideal Transcript:

To thrive in this role, you’ll need:

• Advanced health/life sciences degree (PhD, PharmD, or MD)
• 10+ years in biopharma Medical Affairs or Scientific Communications, experience with one-time curative intent therapies and early clinical phase development preferred
• Successful record of achieving and maintaining compliance with all applicable regulatory, legal, and operational rules
• Demonstrated experience building productive relationships with internal stakeholders and external stakeholders including KOLs and patient advocacy groups
• Excellent written and oral communication skills with the ability to influence senior leadership, cross-functional partners, and external stakeholders.
• Capacity to critically analyze and interpret complex scientific data and translate it into medical strategy
• Track record of planning, initiating, and completing high-impact projects within established timelines.
• History of thriving in ambiguity, managing multiple priorities while maintaining focus on achieving defined objectives