Senior Director, Oncology Small Molecule

Responsibilities

• Develop and execute a forward-thinking pipeline strategy, shaping the future of our Company's Oncology therapeutics with a focus on small molecules.
• Be a strategic thought leader for the employment of small molecules to create effective, tolerable, and combinable medicines that are both first-in-class and best-in-class.
• Leverage deep understanding of cancer biology and the current internal and external oncology landscape to evaluate the opportunity of new therapeutics and drive portfolio decisions.
• Provide strategic oversight for programs as they transition from early discovery into and through late-stage clinical development.
• Drive key milestones for pipeline advancement, from preclinical candidate selection through to IND-enabling studies and support for early clinical development.
• Ensure compelling engagement with regulatory agencies.
• Lead business development evaluations from a scientific perspective, identifying and championing external assets and platforms.
• As a member of the Discovery Oncology Leadership team, contribute to strategy and the growth and development of staff.
• Act as an experienced Program Lead and mentor others to become strong Program Leaders.
• Foster a high-performance culture of collaboration, engagement, self-accountability, and inclusion.
• Establish strong relationships within highly collaborative, multidisciplinary teams to drive drug discovery initiatives.

Required Qualifications / Education

• Ph.D. in Biology, Oncology, Pharmacology, Biochemistry, Toxicology, Biophysics, Immunology, or a related STEM subject area with 10+ years of post-degree experience in industry or equivalent.
• An extensive background in cancer biology with a proven ability to translate deep scientific insights into drug development strategies from discovery through late-stage development.
• Evidence of innovative approaches to small molecule design, particularly induced proximity.
• A proven track record of successfully advancing multiple well-designed investigative small molecule drug candidates into the clinic.
• Clear experience in late program leadership partnering with regulatory, translational sciences, and clinical development.
• Direct, hands-on experience writing IND modules and filings.
• Experience managing a group of senior and junior scientists with a track record of achievements, including project leadership and strategic contributions.
• Ability to build strong relationships within highly collaborative, multidisciplinary teams.
• Excellent attention to detail and strong communication (oral and written) skills.
• Highly self-motivated and capable of prioritizing deliverables.

Preferred Experience and Skills

• Preference will be given to candidates with a large breadth of small molecule experience, including novel approaches.
• Experience with modalities beyond traditional small molecules is beneficial, particularly including small molecule payloads.