Senior Director, Pharmacokinetics

This leader will be accountable for shaping and executing fit-for-purpose bioanalytical strategies, enabling high-quality, timely data packages that support molecular design, candidate selection, translational interpretation, regulatory readiness, and portfolio decision-making.

Key Responsibilities

• Provide scientific and portfolio leadership for bioanalytical strategy across discovery programs, ensuring fit-for-purpose assay execution, data quality, compliance, and decision-making impact across biologics, conjugates, peptides, small molecules, and other emerging modalities.
• Drive operational excellence through workflow optimization, resource and capacity planning, automation, digital tools, data systems, and continuous improvement of bioanalytical processes.
• Promote harmonization and knowledge sharing across bioanalytical teams, sites, and external partners to improve consistency, flexibility, and responsiveness to changing portfolio needs.
• Monitor external scientific, technology, and regulatory trends in bioanalysis and related disciplines, and champion evaluation and implementation of new methodologies and best practices.
• Manage a team of DMPK team representatives, bioanalytical leaders/scientists, setting clear scientific expectations and enabling effective prioritization, execution, and career development.
• Represent PDMB on cross-functional discovery and development teams, integrating bioanalytical, ADME, PK/PD, translational, and regulatory perspectives to guide program decisions.
• Ensure PDMB deliverables support molecular design, lead optimization, candidate selection, nonclinical-to-clinical translation, first-in-human enablement, regulatory submissions, and clinical development planning.
• Serve as a scientific advisor or principal investigator for programs, platform initiatives, or cross-functional scientific workstreams.
• Build and maintain effective partnerships with discovery, development, translational, clinical, regulatory, and external collaborators to enable integrated pipeline support.
• Review, author, and present scientific documents, regulatory sections, technical reports, portfolio updates, and decision-making materials for internal and external stakeholders.
• Foster a culture of innovation, accountability, collaboration, inclusion, safety, quality, and compliance.

Qualifications

Education: Master's (with 15+ years) or Ph.D. (with 12+ years) in pharmacokinetics, pharmaceutical sciences, bioanalytical chemistry, analytical chemistry, biochemistry, biology, pharmacology, immunology, bioengineering, or a related scientific discipline with significant experience in bioanalytical sciences, DMPK, drug discovery and development.

Required Experience and Skills

• Demonstrated scientific and operational leadership in bioanalysis, including assay strategy, method development, validation or qualification, sample analysis, data interpretation, and reporting.
• Track record demonstrating strong understanding of bioanalytical approaches relevant to biologics, conjugates, peptide, small molecule, and novel therapeutic modalities.
• Proven experience participating in cross-functional discovery and development program teams.
• Proven ability to integrate bioanalytical, ADME, PK, PK/PD, translational, toxicology, clinical pharmacology, and regulatory considerations to support program decisions.
• Demonstrated ability to manage a portfolio of programs by early strategy formation, prioritizing resources, aligning deliverables with milestones, identifying risks, and ensuring high-quality scientific execution.
• Demonstrated ability to develop DMPK representatives, bioanalytical leaders/scientists by strengthening scientific judgment, project-team leadership, communication, and decision-making impact.
• Proven people leadership experience, including management, mentoring, talent development, performance management, and building high-performing scientific teams.
• Demonstrated ability to lead through change, shape organizational capabilities, and develop future scientific and people leaders.
• Excellent written and verbal communication skills, with the ability to present complex scientific and operational topics clearly to technical, cross-functional, and senior leadership audiences.
• Strong collaboration and influencing skills, with demonstrated ability to build effective partnerships across functions, sites, and external organizations.
• Commitment to quality, safety, compliance, scientific rigor, operational excellence, and inclusive leadership.

Preferred Experience and Skills

• Demonstrated ability to modernize workflows through automation, digital tools, data systems, assay harmonization, process improvement, or innovative bioanalytical technologies.
• Experience serving as scientific representative, or functional leader accountable for cross-function and/or cross-site collaboration.
• Familiarity with translational PK/PD, exposure-response, human dose projection, biomarker strategy, biodistribution assessment, immunogenicity risk assessment, or model-informed drug development.
• Experience supporting or leading programs involving drug conjugates, multispecific biologics or peptides, or other complex and emerging modalities.
• Working knowledge of cell-based assays, biophysical or biochemical characterization.
• Track record of scientific visibility through publications, conference presentations, external collaborations, consortia participation, or cross-industry engagement.