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Senior Global Brand Director panKRAS

AstraZeneca

Gaithersburg, MDOnsitePosted 16 days ago$231,988.80 - $347,983.20/year
Full TimeDirector & AboveCommercial & Pharma SalesPharmaceutical
Original posting ↗

Summary

PanKRAS represents one of the most exciting growth opportunities within AstraZeneca's GI Oncology portfolio and is expected to play a pivotal role in our ambition to lead in Pancreatic, Colorectal, and Lung cancer. As Senior Director, Global Commercial, panKRAS, you will lead the global commercial strategy for AstraZeneca's panKRAS asset, a clinical stage, oral, multi-target KRAS inhibitor, with the potential to transform outcomes for patients across multiple tumor settings where KRAS is considered to be a relevant clinical target.

Job description

The Senior Director, Global Commercial, panKRAS will be part of the Global IO Commercial Franchise Team and will set and implement the global commercial strategy for this priority asset. Reflecting the asset's earlier stage of development, the role will provide proactive commercial and strategic input to development priorities and decisions, working closely with Clinical Development, Global Medical Affairs, Regulatory Affairs, Diagnostics, Pricing and Market Access, Global Analytics & Insights, Digital, Corporate Affairs, regional and country teams, and other partners.

Typical Accountabilities | Job Responsibilities

1. Global brand strategy and leadership

  • Set and communicate a clear, differentiated and long-term global brand strategy for our panKRAS asset, aligned with the GI tumour strategy and broader Oncology priorities.
  • Lead annual strategic and operational planning, including positioning, segmentation, customer strategy, value proposition, target market selection and lifecycle priorities.
  • Generate deep customer, patient, market and competitive insights and translate them into choices that address unmet need and maximise value.
  • Provide proactive commercial and strategic input to development priorities and decisions, including indication and patient-segment prioritisation, target product profile, evidence-generation needs, clinical development trade-offs and key investment choices.
  • Develop future-focused revenue forecasts and business cases informed by robust insights and sound commercial judgement.
  • Represent Global Commercial in relevant Global Product Team, development and investment decision forums, providing commercially rigorous input to evidence generation, clinical development strategy, stage-gate decisions and Phase III investment choices.

2. Launch excellence and market shaping

  • Lead global launch strategy, launch readiness and execution for panKRAS across priority markets, with clear milestones, decision points and performance measures.
  • Engage regional and country teams early, incorporate market feedback and establish mechanisms to share learning and accelerate adoption of best practice.
  • Lead agency and vendor relationships, ensuring quality, pace, compliance, value and effective use of resources.

3. Business, budget and performance management

  • Own and manage relevant global brand budgets, forecasts and resource allocation to target, with clear prioritization and financial discipline.
  • Define a focused performance framework and use leading and lagging measures to identify gaps, risks and opportunities.
  • Provide high-quality brand and business updates to senior leadership, generating clear decisions and follow-through.
  • Proactively identify and manage strategic, operational, regulatory and reputational risks, ensuring activities comply with policy, legal, regulatory and industry requirements.

Education, qualifications, skills and experience

Essential:

  • Relevant experience in pharmaceutical development and commercialization, with strong oncology commercial experience.
  • Proven pre-launch and launch excellence capability, including creation and execution of global brand strategies and campaigns.
  • Strong strategic marketing, customer insight, forecasting, market research, competitive analysis, and business-case skills.
  • Strong clinical and scientific acumen, with the ability to translate complex evidence into clear commercial choices.
  • Demonstrated success leading cross-functional teams in a global matrix and influencing laterally and vertically.
  • Strong business and financial acumen, including budget and agency management.
  • Exceptional written, verbal and presentation skills, with the ability to communicate clearly to senior leaders and diverse markets.
  • Enterprise mindset, high ethical standards, personal integrity, urgency, and the ability to deliver with a high degree of autonomy.

Desirable:

  • GI Oncology, pancreatic or colorectal cancer, or biomarker-driven therapy experience.
  • Advanced degree in business, science or related field; MBA preferred.
  • Sales, customer-facing, or market access experience.
  • Formal people-management experience.
  • Experience supporting late-stage development, Phase III investment decisions, or lifecycle strategy.

Minimum qualifications: Bachelor's Degree in relevant field. 10+ years' experience in pharmaceutical and/or healthcare industry with experience in one or more of the following: brand marketing, sales, market research/analytics, strategic planning.

Requirements

  • Bachelor's Degree in relevant field
  • 10+ years' experience in pharmaceutical and/or healthcare industry
  • Relevant experience in pharmaceutical development and commercialization
  • Strong oncology commercial experience
  • Proven pre-launch and launch excellence capability
  • Creation and execution of global brand strategies and campaigns
  • Strong strategic marketing skills
  • Customer insight skills
  • Forecasting skills
  • Market research skills
  • Competitive analysis skills
  • Business-case skills
  • Strong clinical and scientific acumen
  • Demonstrated success leading cross-functional teams in a global matrix
  • Influencing laterally and vertically
  • Strong business and financial acumen
  • Budget and agency management
  • Exceptional written, verbal and presentation skills
  • Enterprise mindset
  • High ethical standards
  • Personal integrity
  • Urgency
  • Ability to deliver with a high degree of autonomy

Benefits

  • Short-Term Incentive Bonus
  • Equity-Based Long-Term Incentive Program
  • Retirement Contribution
  • Commission Eligibility

Company overview

AstraZeneca is a global, science-led, patient-focused pharmaceutical company dedicated to accelerating the delivery of life-changing medicines that create enduring value for patients, society, and shareholders. With a workforce of over 94,300 employees worldwide, the company operates across three core therapy areas: Oncology, BioPharmaceuticals (including Cardiovascular, Renal & Metabolism, Respiratory & Immunology), and Rare Disease. Headquartered in Cambridge, UK, AstraZeneca maintains strategic R&D centers in Cambridge, Gaithersburg (US), Boston (US), Gothenburg (Sweden), Shanghai, and Beijing. The company generated $54.1 billion in total revenue in 2024 and invested $13.6 billion in scientific research and development. AstraZeneca's bold aspiration is to be pioneers in science, lead in disease areas, and transform patient outcomes, with a goal to launch 20 new medicines and achieve $80 billion in total revenue by 2030. The company is recognized for its commitment to sustainability, health equity, and creating an inclusive work environment where diverse perspectives drive innovation.

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