Monte Rosa Therapeutics, Inc logo

Senior Manager FP&A

Monte Rosa Therapeutics, Inc

Boston, MAOnsitePosted 25 days ago$130,000 - $155,000/year
Full TimeSenior LevelCorporate FunctionsBiotechnology
Original posting ↗

Summary

We are seeking a Senior Manager, FP&A to join our Boston-based Finance team. Reporting to the Director, FP&A, this individual will support and own planning, forecasting, and analytics across a significant portion of the Company's operating expense base, partnering directly with department leaders to translate strategic priorities into credible financial plans.

Job description

Overview

We are seeking a Senior Manager, FP&A to join our Boston-based Finance team. Reporting to the Director, FP&A, this individual will support and own planning, forecasting, and analytics across a significant portion of the Company's operating expense base, partnering directly with department leaders to translate strategic priorities into credible financial plans.

This is a broad, high-visibility role with exposure to both our scientific organization and our corporate functions. You will be a core contributor to the annual planning cycle, quarterly reforecasts, monthly close, cash and runway analysis, and Board-level reporting. The scope is intentionally wide — we are looking for someone who wants to understand how the whole company works, not just one slice of it.

Responsibilities

  • Own the annual operating plan, quarterly reforecasts and long-range plan for assigned areas.
  • Build and maintain driver-based models for headcount, personnel costs, external spend, consumables, capital and allocations.
  • Prepare monthly and quarterly reporting packages with budget-versus-actual variance analysis, including forward-looking commentary on the full-year outlook.
  • Contribute to cash forecasting, burn analysis and runway management; support financing planning, Board materials, budget presentations and external operating expense guidance.
  • Build financial models and decision support for CRO/CDMO and vendor contracts, collaborations, capital equipment, software and facilities; evaluate resource allocation trade-offs across programs, platforms and infrastructure.
  • Model headcount plans, compensation cycles, recruiting plans and payroll/benefits forecasts with People Experience & Operations.
  • Work with Accounting on accruals, reclasses and spend validation; check that expense classification follows policy and external reporting requirements.
  • Improve FP&A processes, reporting templates and self-service reporting in NetSuite and planning tools; support internal controls, SOX-readiness and audit requests on budgeting and forecasting.

Qualifications

  • Bachelor's degree in Finance, Accounting, Economics or a related quantitative field.
  • 7–10+ years of progressive FP&A, corporate finance or accounting experience.
  • Demonstrated ownership of multiple full budget and forecast cycles for meaningful cost centers, including direct work with senior non-finance leaders.
  • Advanced Excel and financial modeling skills, able to build a clean, auditable, flexible model from a blank sheet.
  • Strong command of accrual accounting and the month-end close process.
  • Preferred: Biotech, pharma or life sciences experience, ideally at a clinical-stage company, with exposure to R&D cost centers.
  • Preferred: Hands-on NetSuite and an EPM/planning tool (e.g., Adaptive), plus familiarity with public company reporting (10-Q/10-K, SOX, Board reporting).

Requirements

  • Bachelor's degree in Finance, Accounting, Economics or a related quantitative field
  • 7–10+ years of progressive FP&A, corporate finance or accounting experience
  • Demonstrated ownership of multiple full budget and forecast cycles for meaningful cost centers, including direct work with senior non-finance leaders
  • Advanced Excel and financial modeling skills, able to build a clean, auditable, flexible model from a blank sheet
  • Strong command of accrual accounting and the month-end close process
  • Preferred: Biotech, pharma or life sciences experience, ideally at a clinical-stage company, with exposure to R&D cost centers
  • Preferred: Hands-on NetSuite and an EPM/planning tool (e.g., Adaptive), plus familiarity with public company reporting (10-Q/10-K, SOX, Board reporting)

Company overview

Monte Rosa Therapeutics is a clinical-stage biotechnology company pioneering the development of highly selective molecular glue degrader (MGD) medicines for patients with serious diseases. Founded in 2018 and headquartered in Boston, Massachusetts with operations in Basel, Switzerland, the company focuses on oncology, autoimmune and inflammatory diseases. Monte Rosa's proprietary QuEEN™ (Quantitative and Engineered Elimination of Neosubstrates) discovery engine combines AI-guided chemistry, diverse chemical libraries, structural biology, and proteomics to rationally design MGDs with unprecedented selectivity. The company has developed the industry's leading pipeline of first-in-class and only-in-class MGDs, with three programs currently in clinical trials. Monte Rosa's innovative approach targets previously undruggable proteins by inducing specific protein degradation, offering potential treatments for diseases that other modalities cannot address. The company maintains strategic collaborations with leading pharmaceutical companies in immunology, oncology, and neurology, and is publicly traded on NASDAQ under the ticker symbol GLUE.

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