Senior Manager Manufacturing – Night Shift Operations Performance & Integration
Amgen
Summary
In this vital role the Night Shift Senior Manager of Manufacturing at Amgen is responsible for establishing and sustaining a strong night-shift operating system that provides off-shift operational direction for Commercial Operations and for Project based Commissioning and Qualification (C&Q) coverage, ensuring the right cross-functional resources are engaged, issues are escalated and resolved with urgency, and manufacturing performance is actively managed across the shift.
Job description
Partners with Engineering, Automation, QA, Technology, Maintenance, Supply Chain/Warehouse, Capital Projects.
Responsibilities
- Serve as the senior Manufacturing integration point across night-shift operations during significant operational events.
- Establish and sustain the night-shift Tier structure, operating cadence, escalation model, and performance-management routines.
- Coordinate Manufacturing, Quality Assurance, Engineering, Automation, Maintenance, Supply Chain/Warehouse, and other site resources required to maintain safe, compliant, and reliable operations.
- Drive escalation of significant resource constraints, technical barriers, competing priorities, or unresolved operational issues to appropriate site or functional leadership.
- Monitor overall night-shift Manufacturing performance across production lines, including downtime, OEE, schedule attainment, recurring interruptions, escalation effectiveness, and chronic losses.
- Partner with the daytime Manufacturing Senior Manager, Continuous Improvement Senior Manager and MFG process Support Senior Manager to identify, prioritize, and execute improvement opportunities across off-shift, including 5S, visual management, standard work, workplace organization, waste reduction, flow improvement, and training operating discipline.
- Provide coaching and situational leadership to Front Line Managers during complex operational events
Basic Qualifications
- Doctorate degree and 2 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
- Master’s degree and 6 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
- Bachelor’s degree and 8 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
- Associate’s degree and 10 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
- High school diploma / GED and 12 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
In addition to meeting at least one of the above requirements, you must have a minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above.
Requirements
- Doctorate degree and 2 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
- Master’s degree and 6 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
- Bachelor’s degree and 8 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
- Associate’s degree and 10 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
- High school diploma / GED and 12 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
- Minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation of resources.
Benefits
- Health insurance
- Dental coverage
- Vision coverage
- Retirement and savings plan
- Life insurance
- Disability insurance
- Annual bonus program
- Stock-based long-term incentives
- Paid time off
Company overview
Amgen Inc. is a leading American multinational biopharmaceutical company headquartered in Thousand Oaks, California, founded in 1980. As one of the world's largest independent biotechnology companies, Amgen specializes in discovering, developing, manufacturing, and delivering innovative human therapeutics. The company focuses on six key therapeutic areas: inflammation, oncology/hematology, bone health, cardiovascular disease, nephrology, and neuroscience. Amgen's portfolio includes blockbuster drugs such as Enbrel for autoimmune diseases, Prolia and XGEVA for osteoporosis, Repatha for cholesterol management, Otezla for psoriasis, and Neulasta for chemotherapy-induced neutropenia. With approximately 28,000 employees worldwide, Amgen operates as a component of both the Dow Jones Industrial Average and Nasdaq-100 indices. The company maintains a robust research and development pipeline with numerous clinical programs across various stages, leveraging cutting-edge biotechnology and human genetic data to address some of the world's most challenging diseases. Amgen's manufacturing capabilities span multiple global locations, and it distributes products through pharmaceutical wholesale distributors and direct-to-consumer channels.