Senior Materials Scientist
Eurofins PSS Insourcing Solutions
Summary
We are seeking a highly innovative Materials Scientist with deep expertise in non-traditional solid-form strategies for beyond Rule-of-5 (bRo5) molecules, including PROTACs, RIPTACs, and molecular glues. This role will support the design of advanced solid form screening approaches, amorphous solid dispersion (ASD) formulations, and predictive mathematical models. The position is based in Groton, CT (USA).
Job description
Role Responsibilities
- Conduct advanced solid-state characterization of large bRo5 molecules of pharmaceutical relevance.
- Apply novel crystallization techniques to recrystallize bRo5 molecules.
- Support multidisciplinary project teams and collaborate with colleagues to define and implement crystallization, polymorph, salt, and co-crystal screening activities according to project timelines.
- Collaborate with colleagues in Medicinal Chemistry, Formulation and Biopharmaceutics to define and implement screening and characterization strategies consistent with solid form selection for clinical studies.
- Solve scientific problems using contemporary Materials Science experimental techniques.
- Contribute to the development of new scientific approaches and knowledge within the Materials Science organization.
- Ensure contemporaneous and accurate entries are made in the electronic laboratory notebook system according to accepted good practice.
Qualifications
- Master's Degree (MS) with 2+ years of experience in a related field.
- Strong pharmaceutical, API, small molecules testing for drug production is required.
- Experience in pharmaceutical solid state characterization techniques (such as x-ray powder diffraction, polarized light microscopy, differential scanning calorimetry, thermogravimetric analysis, spectroscopy, etc.). Strong data analysis and interpretation skills.
- Experience and understanding of infrared spectroscopy (FTIR, NIR, FT-Raman) and/or SSNMR.
- Experience with solving Materials Science problems related to large molecules, e.g., solid state chemistry and particle characterization using experimental approaches and team collaboration.
- Experience with amorphous solid dispersion strategies and ability to develop innovative solid form screening strategies.
- Understanding of physical, analytical, and organic chemistry.
- Good organizational skills, the ability to work independently, and excellent oral and written communication skills are required.
- Experience in mathematical modeling.
The position is full-time, M-F 8 am to 5 pm. May be requested to work on weekends, overtime, and holidays based on business needs. Candidates currently living within a commutable distance of Groton, CT are encouraged to apply.
Requirements
- Master's Degree (MS) with 2+ years of experience in a related field
- Strong pharmaceutical, API, small molecules testing for drug production
- Experience in pharmaceutical solid state characterization techniques (X-ray powder diffraction, polarized light microscopy, differential scanning calorimetry, thermogravimetric analysis, spectroscopy)
- Strong data analysis and interpretation skills
- Experience and understanding of infrared spectroscopy (FTIR, NIR, FT-Raman) and/or SSNMR
- Experience solving Materials Science problems related to large molecules, solid state chemistry and particle characterization
- Experience with amorphous solid dispersion strategies and innovative solid form screening strategies
- Understanding of physical, analytical, and organic chemistry
- Good organizational skills and ability to work independently
- Excellent oral and written communication skills
- Experience in mathematical modeling
Benefits
- Medical, Dental & Vision
- Life & Disability Insurance
- 401(k) Matching
- Paid Vacation
- Paid Holidays
Company overview
Eurofins PSS Insourcing Solutions is a global, award-winning managed service provider specializing in scientific workforce solutions for the life sciences industry. As part of the Eurofins Scientific group, the company offers innovative insourcing models that place dedicated scientific teams directly at client sites to manage laboratory operations and testing services. With over 20 years of experience, PSS employs and manages full-time scientific professionals who work within client facilities using their equipment, quality systems, and methodologies. The company serves pharmaceutical, biotechnology, and medical device companies across nearly 20 countries, providing services spanning the entire drug development pipeline from early discovery to finished product testing. Their unique model eliminates co-employment concerns while offering clients flexible, cost-effective workforce solutions that typically outperform traditional temporary staffing arrangements. Eurofins PSS has grown to employ over 1,800 professionals at more than 70 client sites worldwide, delivering specialized services in analytical chemistry, microbiology, process development, quality control, and various other scientific disciplines.