Senior Process Engineer
AstraZeneca
Summary
We are seeking a Senior Process Engineer to join our GPD Process Technology and Engineering Unit, supporting the development of innovative inhaled and/or oral solid dosage products.
Job description
In this role, you will lead key process engineering activities across an exciting portfolio of programs spanning early through late-stage development. As part of a multidisciplinary team, you will help shape product development strategies, design and execute laboratory and pilot-scale work packages, and advance the use of in silico tools to accelerate development and strengthen process understanding.
We are looking for a collaborative, solutions-focused engineer who thrives in a fast-paced scientific environment. You will play an important role in developing robust, well-understood, and well-controlled manufacturing processes designed to support long-term commercial performance and patient needs.
Key Responsibilities
- Lead engineering work packages focused on the design and development of robust manufacturing processes for oral and inhaled products.
- Plan and execute lab-scale process development experiments to generate insights and inform key project decisions.
- Help shape the scientific and technical direction of product development through strong process understanding and control.
- Define and optimize critical process parameters (CPPs) and integrate them into effective control strategies.
- Lead or contribute to technology transfer, risk assessment, process validation, and scale-up activities.
- Apply modelling, simulation, digital twins, and predictive tools to strengthen process understanding and accelerate development.
- Identify and solve complex technical challenges that directly impact project delivery.
- Champion a culture of creativity, innovation, collaboration, and scientific excellence.
- Partner across functions and take ownership of technical work packages, contributing to integrated drug product development plans within a multidisciplinary team and under the guidance of senior staff.
Essential Skills and Experience
- Bachelors Degree in Related Discipline (e.g - Chemical Engineering, Chemistry, or related field) with at least 3 years of relevant industry experience
- Experience in oral solid dose and/or inhaled drug product development.
- Experience in early to late stage product development, technology transfer, scale up and process validation.
- Fundamental understanding of control strategy and risk management.
- Basic understanding of predictive science, artificial intelligence, modelling and simulation.
- Demonstrated understanding and application of digital tools and process models for development
- Excellent communication and collaboration skills
Desirable Skills and Experience
- Masters or PhD in related discipline
- Experience with manufacturing processes and technologies relevant to oral solid dosage and/or inhaled products
- Direct compression/wet granulation/roller compaction tableting
- Spray drying particle engineering
- pMDI or DPI manufacturing
- Experience with regulatory authoring and defense.
- Experience with CMOs/CROs and outsourced development.
- Experience with regulatory submission authoring
- Process modelling / Digital twin development
Requirements
- Bachelors Degree in Related Discipline (e.g - Chemical Engineering, Chemistry, or related field) with at least 3 years of relevant industry experience
- Experience in oral solid dose and/or inhaled drug product development.
- Experience in early to late stage product development, technology transfer, scale up and process validation.
- Fundamental understanding of control strategy and risk management.
- Basic understanding of predictive science, artificial intelligence, modelling and simulation.
- Demonstrated understanding and application of digital tools and process models for development
- Excellent communication and collaboration skills
Company overview
AstraZeneca is a global, science-led, patient-focused pharmaceutical company dedicated to accelerating the delivery of life-changing medicines that create enduring value for patients, society, and shareholders. With a workforce of over 94,300 employees worldwide, the company operates across three core therapy areas: Oncology, BioPharmaceuticals (including Cardiovascular, Renal & Metabolism, Respiratory & Immunology), and Rare Disease. Headquartered in Cambridge, UK, AstraZeneca maintains strategic R&D centers in Cambridge, Gaithersburg (US), Boston (US), Gothenburg (Sweden), Shanghai, and Beijing. The company generated $54.1 billion in total revenue in 2024 and invested $13.6 billion in scientific research and development. AstraZeneca's bold aspiration is to be pioneers in science, lead in disease areas, and transform patient outcomes, with a goal to launch 20 new medicines and achieve $80 billion in total revenue by 2030. The company is recognized for its commitment to sustainability, health equity, and creating an inclusive work environment where diverse perspectives drive innovation.