Senior Product Manager, Digital Products

Essential Duties and Responsibilities

• Build and own the roadmap to deliver the product strategy for digital experiences, translating long-term vision into prioritized quarterly outcomes with explicit success metrics, and contribute the customer insight and market evidence that sharpens that strategy over time
• Lead end-to-end product execution, from requirements and acceptance criteria through scope trade-offs, launch readiness, staged rollout, and post-launch optimization, ensuring delivery against customer, business, and quality objectives.
• Identify and prioritize opportunities to simplify core workflows—including ordering, task management, results comprehension, and scheduling—using customer insights and data to reduce friction and improve completion, comprehension, and satisfaction.
• Develop and optimize product growth loops across entry points, activation, self-service, and notification-driven re-engagement, establishing hypotheses and measurable targets for adoption, conversion, and retention.
• Define and champion the quality bar for AI-enabled experiences, defining evaluation criteria, safeguards, transparency standards, and launch thresholds appropriate for physician- and patient-facing use cases.
• Define and instrument the product metric tree before launch; use funnel, cohort, experimentation, and qualitative insights to guide decisions, evaluate impact, and maintain rigor in interpreting results.
• Partner deeply with Design and Engineering to shape information architecture, user flows, prototypes, and technical trade-offs; provide substantive product critique and embed accessibility, performance, and scalability into product requirements.
• Influence portfolio-level investment and prioritization decisions, using customer and business evidence to recommend where Guardant should invest, accelerate, or deprioritize.
• Use AI-enabled tools to rapidly prototype, test, and refine product concepts, accelerating learning and improving the quality of decisions before committing design and engineering capacity.
• Influence and align partners across Medical Affairs, Compliance, Quality, Lab Operations, Commercial, Design, and Engineering, proactively incorporating regulatory, design-control, governance, and operational requirements into product plans.

Qualifications

• Typically bachelor’s with ~12+ years (or 8+ with master’s / 5+ with PhD / 3+ with PharmD/MD).
• 5+ years in product management with 3+ years owning external, user-facing web or mobile products end to end.
• Track record of launching and scaling user-facing products with quantified outcomes in adoption, conversion, or retention, and the specifics of what you did to move them.
• Demonstrated product-led growth experience: acquisition and activation funnels, onboarding, self-service, and lifecycle messaging.
• Strong working knowledge of modern front-end and mobile technology - JavaScript frameworks, design systems, responsive design, API patterns, performance, accessibility- sufficient to hold a real trade-off conversation with senior engineers.
• Hands-on fluency in product analytics and experimentation (Pendo, Amplitude, or similar); comfortable writing queries to interrogate data.
• Works AI-natively: uses modern AI tooling to prototype flows, pressure-test concepts, and synthesize research, and moves faster because of it rather than waiting on design and engineering cycles.
• Experience owning a product surface with non-deterministic output - setting acceptance criteria and evaluation for quality, and designing for the cases where the system is wrong.
• Excellent written communication and a proven ability to ship inside shared engineering capacity, legacy systems, and competing stakeholder priorities.

Preferred Qualifications

• Experience in healthcare, digital health, or another regulated environment (HIPAA/PHI, FDA, CLIA/CAP, SOC 2).
• Familiarity with clinician workflow and EMR/EHR integration (HL7 v2, FHIR, SMART on FHIR, Epic).
• Experience with clinical decision support or other high-stakes recommendation experiences.