Senior Product Manager, Provider and RWD Health Systems Applications
Natera
Summary
Natera's RWD platform at the clinic connects an ecosystem of real-world evidence, molecular data, and clinical insights to deliver actionable information to physicians. We are seeking a Senior Product Manager to help build and scale physician-facing RWD applications. We seek to unlock the full potential of real-world data to improve treatment outcomes and make molecular results actionable in everyday treatment decisions. In this role, you'll own a physician-facing RWD application for a patient's molecular and clinical journey and workflow integrations behind it, partnering with cross-functional product teams, engineering, AI/ML teams, and clinical teams to deliver intuitive tools centered on enriched patient insights.
Job description
What You'll Do
Advance Data Integration and Intelligence
- Collaborate with clinical product management, EMR, user experience product management, marketing, medical and a broad cross functional team to drive product strategy and roadmap
- Drive integration of genomic tests into the platform (Signatera/ctDNA, hereditary risk, tumor/normal and NGS profiling, liquid CGP, etc.) as part of a unified oncology digitized experience.
- Work closely with AI/ML teams to build applications for patient-level insights and clinic-level insights, including cohort comparison, clinical trial matching, and cohort analytics back to individual patient care.
- Partner with legal, privacy, and security so HIPAA obligations, PHI handling, and data-governance requirements are designed into the product.
Elevate the User Experience
- Own the single- and multi-patient views that bring a patient's molecular results and clinical events together in one physician-facing application.
- Integrate AI-powered clinical trial matching that connects patients and physicians to the most relevant investigational therapies based on molecular, clinical, and patient criteria.
- Help reduce friction points at both the provider and patient level to enroll in clinical trials.
- Partner across Natera to enable EMR/EHR integration and mobile access, ensuring seamless experiences for providers.
- Contribute to an analytics framework that captures user analytics and informs continuous product development.
Enhance the Utility of Genomic Testing
- Support delivery of a physician-facing platform that highlights therapies, tracks treatment response, and monitors disease progression in real time.
- Ship tools and functionality to aid physician collaboration.
- Connect molecular and clinical findings to relevant treatment pathways and outcomes data to make testing more actionable at the point of care.
- Partner with Product Marketing, MSL, Sales, and Clinical Operations on enablement, training, and adoption.
Launch the De-Identified Aggregated Research Platform for Health Systems
Partner with the Health Systems BU to define, build, and launch a de-identified, aggregated research platform that turns clinic data into a health-system-wide resource for precision medicine and research.
Engage Key Stakeholders
- Engage with physicians, KOLs, and academic collaborators to translate clinical needs into features.
- Help track KPIs centered on the physician experience with RWD at the clinic.
- Support representation of RWD at the clinic at conferences, industry forums, and customer discussions as needed.
Requirements
- 5+ years of product management or related experience, including experience in healthcare, engineering, genomics, or AI/ML.
- Deep understanding of the oncology domain with direct experience building requirements and collaborating with physicians.
- Experience building clinician-facing software that fits into real clinical workflows.
- Experience delivering AI/LLM-derived clinical data into provider-facing products, including human-in-the-loop review, confidence labeling, and data transparency.
- Backlog ownership: writing and grooming user stories in Jira and driving PM perspective in Agile ceremonies (sprint planning, standups, retros).
- Hands-on with data: comfortable writing SQL (or equivalent) to check status, investigate issues, and measure outcomes, and in the habit of asking 'is this correct, and are we ready to ship?'
- Track record of setting product KPIs and moving them, with specifics on adoption, engagement, and quality.
- Fluency in oncology / genomics clinical concepts (staging, lines of therapy, biomarkers, MRD/ctDNA).
- Commitment to user-centered design thinking, with a track record of translating user needs into intuitive and impactful product experiences.
- Strong written and verbal communication skills with clinical, technical, and commercial audiences.
- Preferred: Using AI tools day to day to prototype and draft specs.
- Preferred: EHR integration experience (SMART on FHIR, HL7/FHIR, Epic or other EHR app ecosystems).
- Preferred: Strong technical fluency; comfortable working with engineers, scientists, and data teams, and reasoning about what AI/ML and LLMs can and can't reliably do.
- Preferred: Familiarity with PHI-handling applications, HIPAA, or regulated clinical software.
- Preferred: Familiarity with FDA clinical decision support or SaMD considerations.
Benefits
- Medical, Dental & Vision
- Life & Disability Plans
- Free Testing
- Fertility Care Benefits
- Pregnancy & Baby Bonding Leave
- 401(k) Benefits
- Commuter Benefits
- Employee Referral Program
Company overview
Natera is a global leader in cell-free DNA (cfDNA) testing, specializing in molecular diagnostics for oncology, women's health, and organ health. Founded in 2004 and headquartered in Austin, Texas, the company has developed a cutting-edge cfDNA technology platform that combines novel molecular biology techniques with bioinformatics software and artificial intelligence. Natera's proprietary technology enables detection down to a single molecule in a tube of blood, making it possible to provide highly accurate genetic testing services. The company's flagship products include Signatera, a personalized circulating tumor DNA test for cancer monitoring; Panorama, a non-invasive prenatal test for chromosomal abnormalities; and Prospera, a transplant rejection assessment test. With over 4,400 employees and operations in CLIA-certified, CAP-accredited laboratories in Austin and San Carlos, California, Natera has processed more than 12 million tests and validated its technology through over 300 peer-reviewed publications. The company went public in 2015 and continues to innovate in precision medicine, aiming to make personalized genetic testing part of standard healthcare to enable earlier interventions and improved patient outcomes.