Senior Research Associate, Analytical Development

Key Responsibilities

• Independently execute analytical methods using UPLC (SEC, IEX, RP), CE (CE-SDS, cIEF), and binding assays (ELISA, BLI) to support antibody characterization, with a high standard of accuracy and reproducibility.
• Support method optimization and qualification activities under the guidance of senior scientists, and contribute to the development of new methods as needs arise.
• Generate data for cell line development, process development, formulation screening, comparability, and stability studies, and manage sample tracking and testing schedules.
• Process, analyze, and summarize data; perform first-pass interpretation and flag unexpected results or trends to project scientists in a timely manner.
• Maintain accurate, complete, and timely documentation in electronic lab notebooks and data systems in line with good documentation practices.
• Perform routine instrument maintenance, calibration checks, and basic troubleshooting for UPLC, CE, plate readers, and BLI instruments; coordinate service and preventive maintenance.
• Prepare reagents, buffers, reference standards, and critical materials; manage inventory and ordering for the analytical lab.
• Draft method protocols, data summaries, and sections of technical reports for review by senior scientists.
• Collaborate with upstream, downstream, and formulation team members in an integrated CMC environment.
• Contribute to building the analytical lab infrastructure as the company scales, including evaluating new consumables, templates, and workflows.

Qualifications

• BS with 5+ years or MS with 3+ years of relevant industry experience (biotech/pharma) in biologics analytical development or a closely related laboratory function.
• Strong hands-on proficiency with HPLC/UPLC (SEC, IEX, or RP) and/or CE (CE-SDS, cIEF) for therapeutic proteins, including routine troubleshooting.
• Hands-on experience with antibody binding assays (e.g., ELISA, SPR, or BLI).
• Working knowledge of antibody structure, common post-translational modifications, and critical quality attributes (CQAs).
• Demonstrated attention to detail, strong organizational skills, and the ability to manage multiple studies in parallel with shifting priorities.
• Good written and verbal communication skills and a track record of effective teamwork.
• Comfortable working in a fast-paced, evolving environment and willing to take on new responsibilities.

Preferred

• Prior experience in a GMP or QC release testing environment, or with method qualification and tech transfer.
• Familiarity with software platforms such as Empower, SoftMax Pro, ForteBio Data Analysis, or JMP.
• Passion for working in a mission-driven environment and building from the ground up.