Senior Research Associate/Associate Scientist, Analytical Development (Contractor)
Asimov
Summary
We are seeking a highly motivated Senior Research Associate or Associate Scientist (Contractor) to join our Analytical Development team for a 6-month contract. In this role, you will run our developability and biophysical screening panel and support routine product-quality (PQ) analytical delivery for our Cell Line Development (CLD) pipeline. You will work hands-on across plate-based and chromatographic assays to characterize antibodies, multispecifics, and other engineered protein formats, generating the data that guides candidate and clone selection.
Job description
About the Role
- Execute the developability and biophysical screening panel at plate scale, including HIC, AC-SINS, DSF, ELISA-based non-specific binding, and SEC, delivering ranked, decision-ready data on candidate molecules.
- Execute routine PQ analytical delivery for CLD programs, including sample preparation, small-scale Protein A purification, and HPLC/UPLC- and capillary electrophoresis-based assays.
- Manage high-throughput processing of CLD and screening samples in 96-well format, including system suitability checks, reference standard handling, and automated liquid handling.
- Partner with method owners to complete installation and qualification of new assays, then take ownership of routine execution, troubleshooting, and performance trending.
- Partner with cross-functional teams to communicate analytical results and insights clearly and manage multiple projects simultaneously.
- Drive continuous process and technical improvements, including SOPs and technical reports, while maintaining accurate laboratory notebooks and electronic records under GLP and safety protocols.
- This role is a full-time, 6-month contract with the potential for extension or conversion to a permanent position.
About You
- B.S. degree in Chemistry, Biochemistry, Biology, or a closely related field with 3+ years of relevant laboratory experience, or an M.S. degree with 1-2 years of relevant experience.
- Hands-on expertise with plate-based assays and microplate readers (e.g., ELISA) and with HPLC/UPLC separations (e.g., SEC, HIC), along with careful small-scale sample preparation for protein analytics.
- Comfortable working in 96-well format at high throughput.
- A proven aptitude for troubleshooting analytical instruments and methods with a proactive, solution-oriented approach.
- Proficient in data interpretation and the use of statistical tools for trending, with strong communication skills.
- Ability to work effectively in a fast-paced, team-oriented environment with meticulous attention to detail and superior organizational skills.
Requirements
- B.S. in Chemistry, Biochemistry, Biology, or closely related field with 3+ years of relevant laboratory experience, or M.S. with 1-2 years of relevant experience
- Hands-on expertise with plate-based assays and microplate readers (e.g., ELISA)
- Hands-on expertise with HPLC/UPLC separations (e.g., SEC, HIC)
- Careful small-scale sample preparation for protein analytics
- Comfortable working in 96-well format at high throughput
- Aptitude for troubleshooting analytical instruments and methods
- Proficiency in data interpretation and statistical tools for trending
- Strong communication skills to present complex data clearly
- Meticulous attention to detail and superior organizational skills
- Ability to work in a fast-paced, team-oriented environment
Company overview
Asimov is a pioneering synthetic biology company that builds tools to program living cells through the integration of mammalian synthetic biology, computer-aided design, and machine learning. Founded in 2017 by bioengineers from MIT and Boston University, the company develops an integrated platform combining cells, genetic tools, AI models, and software to design and manufacture next-generation therapeutics including biologics, cell/gene therapies, and RNA-based treatments. Headquartered in Boston, Massachusetts, Asimov's mission is to advance humanity's ability to design living systems, enabling biotechnologies with significant societal benefit. The company has raised over $200 million from top investors including Andreessen Horowitz, CPP Investments, Horizons Ventures, and Fidelity Management & Research Company, and has partnered with over 25 companies ranging from small biotechs to major pharmaceutical firms. Asimov's platform includes specialized systems like CHO Edge for biologics production, LV Edge for lentiviral vector manufacturing, and AAV Edge for gene therapy development, consistently delivering high-titer cell lines for advanced therapeutic applications.