Senior Scientist Bioscience
Zenith LifeScience
Summary
We are seeking a highly motivated, lab-based biologist to join our group as a contractor. In this 6-month position, you will support our dynamic and collaborative cross-functional team working on small molecule drug discovery projects within Oncology. You will contribute to the development of cell-based assays, study Client biological mechanisms, identify lead molecules, and elucidate their underlying mechanisms of action. These activities will help progress oncology drug candidates toward clinical evaluation. This contract offers a unique opportunity to work on a diverse range of scientific projects and collaborate with scientists across disciplines in a matrixed environment, making a tangible impact on our oncology programs.
Job description
Major Responsibilities
- Validate oncology target biology using preclinical models such as cell lines and organoids, and generate derivative models using genetic approaches.
- Assay Development: Develop, implement, and troubleshoot cell-based phenotypic assays including proliferation, survival, cell cycle, and apoptosis across 2D/3D and clonogenic formats.
- Experimental Design & Execution: Design and conduct experiments to understand mechanisms of action and identify candidate biomarkers utilizing western blotting, ELISA, flow cytometry, RT-PCR, and high-content imaging approaches.
- Data Analysis & Communication: Analyze, interpret, and effectively communicate experimental data within the team and across projects.
- Record Keeping & Data Generation: Maintain clear and accurate records in accordance with best practices, including data generation for AI application and deployment.
Requirements
- Bachelors or Masters degree in biology or a relevant scientific field with 6+ years post-graduation research experience, or PhD with 2+ years post-graduation research experience.
- Demonstrated skill in data generation, management, and analysis.
- Positive, collaborative attitude and a strong willingness to learn.
- Ability to work independently to execute experiments, identify key scientific questions, and analyze data.
Preferred Background
- Expertise in cancer cell biology and genetics.
- Drug discovery experience in academic, biotech, or pharmaceutical settings.
- Broad assay platform familiarity and experience with assay development or automation.
- High-throughput data generation experience, with the ability to analyze such large-scale datasets.
Additional Information
- This is a temporary contractor position for a defined 6-month term.
- Contractor will be expected to work on-site at our Cambridge, MA location and integrate closely with our project teams.
- Potential for contract extension or transition to other opportunities is subject to business needs.
Requirements
- Bachelors or Masters degree in biology or a relevant scientific field with 6+ years post-graduation research experience, or PhD with 2+ years post-graduation research experience.
- Demonstrated skill in data generation, management, and analysis.
- Positive, collaborative attitude and a strong willingness to learn.
- Ability to work independently to execute experiments, identify key scientific questions, and analyze data.
Company overview
Zenith LifeScience is a premier Contract Research Organization (CRO) and specialized consulting firm based in South Plainfield, New Jersey, providing comprehensive end-to-end clinical development services to the life sciences and healthcare industries. The company operates as both a consulting firm and contract staffing organization, offering integrated clinical research support and lifecycle management services. Zenith LifeScience leverages innovative technologies and therapeutic expertise to help clients optimize drug development timelines and costs while delivering life-changing therapies. Their core service areas include pharmaceutical validation, regulatory affairs, pharmacovigilance and drug safety, clinical data management, clinical trial operations, quality assurance, and compliance. With a team of 51-200 employees, the company emphasizes quality commitment and invests in professional development to ensure client success. Zenith LifeScience serves as a strategic partner for pharmaceutical and biotechnology companies seeking to accelerate clinical development programs while maintaining regulatory compliance and operational excellence.