Senior Scientist
Bristol Myers Squibb
Summary
The Senior Scientist position will be part of the Scale-up Lab based in Devens, MA and reports to the Director of Pilot Plant Network and External Manufacturing (PPNE). The candidate will be responsible for scale-up and execution of upstream and downstream processes for all assets within the Biologics Development portfolio. The candidate will work closely with the process, analytical and manufacturing teams to improve internal process tech transfer procedures and collaborate on new technology initiatives. In addition, the individual will provide support (on as-needed basis) to external GMP-related activities (investigations, deviations, CAPA, change control) within BD’s external portfolio. Prior experience with Pilot, Manufacturing or Biologics Process development is a plus.
Job description
Key Responsibilities
- Lead/support daily operations in the Scale-up Lab, including bioreactor fill/harvest, inoculation, sampling, feeding, operating chromatographic and filtration skids, buffer preparation, run monitoring/troubleshooting
- Prepare/review technical documents including campaign summary reports and batch records
- Participate in cross-functional teams to support process investigations, process development, scale-up, and tech transfer to clinical and commercial manufacturing
- Introduce, evaluate, and implement innovative new process technologies and capabilities
- Identify and implement process transfer improvement initiatives with internal stakeholders
- Support GMP-related activities for BD External Manufacturing programs (as needed)
- Maintain a safe work environment in the Scale-up lab
- Works with an operational excellence mindset
Qualifications
- Ph.D. with 2-4 years experience, M.S. with 4-6 years experience or B.S. with 7-9 years experience in Chemical/Biochemical Engineering, Biochemistry, or related field with relevant industrial and/or academic experience
- Strong knowledge of either Upstream Processing (Mammalian Cell Culture) or Downstream Processing (Harvest, Chromatography and Filtration)
- Working knowledge of cGMP
- Excellent oral and written communication skills
- Works well in a team and as an individual
- Prior experience in single-use manufacturing and automation. Working knowledge of cGMP is a plus
- Knowledge of statistics, design of experiment, and data analysis is desired
Requirements
- Ph.D. with 2-4 years experience, M.S. with 4-6 years experience or B.S. with 7-9 years experience in Chemical/Biochemical Engineering, Biochemistry, or related field with relevant industrial and/or academic experience
- Strong knowledge of either Upstream Processing (Mammalian Cell Culture) or Downstream Processing (Harvest, Chromatography and Filtration)
- Working knowledge of cGMP
- Excellent oral and written communication skills
- Works well in a team and as an individual
- Prior experience in single-use manufacturing and automation
- Knowledge of statistics, design of experiment, and data analysis
Benefits
- Wellbeing support
- Retirement benefits
- Financial protection benefits
- Medical insurance
- Dental insurance
- Vision insurance
- Life insurance
- Disability insurance
- Flexible Time Off
- Paid company holidays
- Paid sick leave
- Paid volunteer days
- Summer hours flexibility
- Leaves of absence
- Annual Global Shutdown
Company overview
Bristol Myers Squibb is a global biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines that help patients prevail over serious diseases. Founded in 1887 and headquartered in Princeton, New Jersey, the company operates with a unique BioPharma strategy that combines the reach and resources of a major pharmaceutical company with the entrepreneurial spirit and agility of a biotech firm. BMS focuses on transformative therapies in key therapeutic areas including oncology, hematology, immunology, cardiovascular disease, and fibrosis. The company has built a sustainable pipeline of potential therapies and leverages translational medicine and data analytics to deliver the right medicine to the right patient at the right time. With over 10,000 employees worldwide, Bristol Myers Squibb maintains a strong commitment to scientific excellence, patient-centric innovation, and global health equity through its foundation. The company's portfolio includes groundbreaking treatments such as Opdivo (nivolumab) for cancer, Eliquis (apixaban) for cardiovascular conditions, and Orencia (abatacept) for autoimmune diseases, among others.