Senior Scientist, Non-Viral Delivery Attribute Sciences
Bristol Myers Squibb
Summary
We are seeking a highly motivated and scientifically curious Senior Scientist, Non-Viral Delivery Attribute Sciences to help shape a growing Attribute Sciences capability and establish the mechanistic understanding that will drive next-generation targeted LNP development. This role brings together cell biology, delivery science, and advanced characterization to define the product attributes and biological mechanisms that govern targeted LNP performance. You will integrate diverse scientific datasets, expand advanced characterization capabilities through emerging technologies, and partner across Research and CMC to translate mechanistic insights into product development and program decisions. The ideal candidate brings strong expertise in cell biology and functional assay development, scientific curiosity across disciplines, and a passion for turning mechanistic understanding into innovative targeted therapeutics.
Job description
Position Summary
We are seeking a highly motivated and scientifically curious Senior Scientist, Non-Viral Delivery Attribute Sciences to help shape a growing Attribute Sciences capability and establish the mechanistic understanding that will drive next-generation targeted LNP development. This role brings together cell biology, delivery science, and advanced characterization to define the product attributes and biological mechanisms that govern targeted LNP performance. You will integrate diverse scientific datasets, expand advanced characterization capabilities through emerging technologies, and partner across Research and CMC to translate mechanistic insights into product development and program decisions. The ideal candidate brings strong expertise in cell biology and functional assay development, scientific curiosity across disciplines, and a passion for turning mechanistic understanding into innovative targeted therapeutics.
Position Responsibilities
- Contribute to the development of the Attribute Sciences function by advancing scientific frameworks and characterization capabilities that underpin non-viral delivery product and platform development.
- Develop biologically relevant cellular characterization strategies, including primary and patient-derived cell systems, to understand how product attributes and biological context influence functional performance.
- Lead attribute characterization supporting formulation and process changes, comparability assessments, and technical investigations, partnering with Analytical Development, Process Sciences, and Product Development to understand impacts on product quality and functional performance.
- Develop and implement high-throughput and automated characterization approaches to improve experimental throughput, reproducibility, and scalability.
- In close partnership with Analytical Development, identify and expand internal and external characterization capabilities for targeted LNP drug products, including emerging technologies and methodologies.
- Collaborate effectively across multidisciplinary Research and CMC functions and represent Attribute Sciences on program and CMC teams, providing scientific expertise to inform product development and program decisions.
- Effectively communicate scientific findings and actionable recommendations to multidisciplinary teams and leadership to influence delivery strategy and program decisions.
- Provide scientific mentorship to junior scientists, and contribute to the development of new experimental approaches and technologies.
Basic Qualifications
- Bachelor’s Degree 7+ years of academic and / or industry experience
- Or Master’s Degree 5+ years of academic and / or industry experience
- Or Ph.D. or equivalent advanced degree in the Life Sciences 2+ of academic and / or industry experience
Preferred Qualifications
- PhD in Cell Biology, Molecular Biology, Immunology, Biochemistry, Bioengineering, Pharmaceutical Sciences, or a related discipline with 2+ years of relevant industry experience; or MS with 5+ years; or BS with 7+ years of relevant experience.
- Strong background in cell biology or a related biological discipline, with demonstrated experience developing and applying cell-based assays to characterize biological activity and functional performance; experience with primary cells, multiparametric flow cytometry, or other advanced cellular characterization approaches.
- Experience with complex drug products, biologics, nanoparticle delivery systems, or related therapeutic modalities is desirable.
- Demonstrated experience applying analytical, biophysical, and cellular characterization approaches to support mechanistic product understanding and establish attribute–performance relationships is preferred.
- Experience with high-throughput, automated, or scalable experimental approaches is preferred.
- Demonstrated ability to work effectively in multidisciplinary teams and thrive in a highly collaborative, cross-functional research environment.
- Strong scientific communication skills, with the ability to present complex data and mechanistic insights clearly and compellingly to diverse audiences including project teams and senior leadership.
Requirements
- Bachelor’s Degree with 7+ years of academic and/or industry experience
- Master’s Degree with 5+ years of academic and/or industry experience
- Ph.D. or equivalent advanced degree in the Life Sciences with 2+ years of academic and/or industry experience
- Strong background in cell biology or a related biological discipline
- Demonstrated experience developing and applying cell-based assays to characterize biological activity and functional performance
- Experience with primary cells, multiparametric flow cytometry, or other advanced cellular characterization approaches
- Demonstrated ability to work effectively in multidisciplinary teams
- Strong scientific communication skills
Benefits
- Wellbeing support
- Retirement benefits
- Financial protection benefits
- Medical, Dental & Vision
- Life & Disability Insurance
- Flexible Time Off
- 11 Paid Company Holidays
- Paid Sick Leave
- Paid Volunteer Days
- Summer Hours Flexibility
- Global Shutdown
Company overview
Bristol Myers Squibb is a global biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines that help patients prevail over serious diseases. Founded in 1887 and headquartered in Princeton, New Jersey, the company operates with a unique BioPharma strategy that combines the reach and resources of a major pharmaceutical company with the entrepreneurial spirit and agility of a biotech firm. BMS focuses on transformative therapies in key therapeutic areas including oncology, hematology, immunology, cardiovascular disease, and fibrosis. The company has built a sustainable pipeline of potential therapies and leverages translational medicine and data analytics to deliver the right medicine to the right patient at the right time. With over 10,000 employees worldwide, Bristol Myers Squibb maintains a strong commitment to scientific excellence, patient-centric innovation, and global health equity through its foundation. The company's portfolio includes groundbreaking treatments such as Opdivo (nivolumab) for cancer, Eliquis (apixaban) for cardiovascular conditions, and Orencia (abatacept) for autoimmune diseases, among others.