Senior Scientist, Translational Research
Triveni Bio
Summary
Triveni Bio is seeking a highly motivated and experienced Scientist to join our Biology and Translational Research team. In this role, you will lead image-based biomarker analyses and drive the experimental design and execution of cell-based and ex vivo preclinical models. This is an exciting opportunity to shape the scientific biomarker strategy across multiple indications, advancing therapeutics that target novel disease pathways.
Job description
Responsibilities
- Lead image-based biomarker analyses using HALO to support biomarker analyses
- Design and execute experimental cell-based and ex vivo preclinical models
- Oversee external research activities, to meet timelines, deliverables, and data quality with Contract Research Organizations (CROs) or academic collaborators
Experience & Qualifications
- Ph.D. in molecular biology or a related discipline with 5+ years of experience within the pharmaceutical or biotechnology sectors.
- Extensive, hands-on expertise in image analysis utilizing HALO.
- Solid background in Immunology and Inflammation indications, with a strong preference for specific experience in atopic dermatitis.
- Familiarity or expertise in mechanistic cell-based and cell-free assays to investigate type 2 immunity, including immune cells, mast cells, IgE biology, cytokine modulation, and other relevant pharmacodynamic readouts.
- Proven track record of effectively managing Contract Research Organizations (CROs), external vendors, and academic collaborators.
Requirements
- Ph.D. in molecular biology or a related discipline
- 5+ years of experience within the pharmaceutical or biotechnology sectors
- Extensive, hands-on expertise in image analysis utilizing HALO
- Solid background in Immunology and Inflammation indications
- Preference for specific experience in atopic dermatitis
- Familiarity or expertise in mechanistic cell-based and cell-free assays to investigate type 2 immunity, including immune cells, mast cells, IgE biology, cytokine modulation, and other relevant pharmacodynamic readouts
- Proven track record of effectively managing Contract Research Organizations (CROs), external vendors, and academic collaborators
Company overview
Triveni Bio is a clinical-stage biotechnology company pioneering a genetics-informed precision medicine approach to develop functional antibodies for the treatment of immunological and inflammatory (I&I) disorders. Founded in 2019 and headquartered in Watertown, Massachusetts, the company leverages advanced antibody engineering to build first-in-class therapeutics that aim to redefine treatment paradigms for complex diseases. Triveni's lead asset, TRIV-509, is a dual-specific monoclonal antibody targeting kallikreins 5 and 7 for the treatment of atopic dermatitis, currently in Phase 2 clinical trials. The company's approach establishes proof-of-concept at the earliest stages of drug development by combining human genetics insights with mechanistic biology to identify novel targets and develop precision medicines. Triveni Bio has raised significant funding, including a $115 million Series B round in 2024, and has been recognized as a Fierce 15 biotech company for its innovative approach to addressing unmet medical needs in dermatology and immunology.