Senior Scientist
Waters Corporation
Summary
Waters Corporation is seeking an accomplished scientific leader to oversee antibody and resin production in support of the VICAM® column production value stream. In this critical role, you will collaborate closely with Research & Development, Engineering, and Manufacturing teams to ensure the reliable, on-time production of antibodies and resins that meet quality, capacity, and operational requirements. The successful candidate will drive process excellence, optimize production performance, and ensure a consistent supply of key materials to support customer demand and the ongoing success of the column production line.
Job description
Responsibilities
Cell Culture Operations
- Retrieve, thaw, and initiate mammalian cell lines from cryogenic storage
- Monitor culture health, morphology, viability, and contamination status
- Perform routine passaging and expansion of cell cultures
- Maintain safety-stock cultures and frozen cell banks
- Perform sterile manipulations within biosafety cabinets
Seed Train Expansion
- Expand cultures through multiple vessel scales to generate inoculum
- Evaluate expansion readiness based on growth phase and culture condition
- Perform aseptic transfers, media additions, and feeding activities
- Maintain proper labeling and tracking of cultures
Bioreactor Setup & Operation
- Install and prepare single-use cultureware systems
- Perform system pressurization testing and leak checks
- Execute fill, flush, and priming procedures
- Perform bioreactor inoculation activities
- Monitor process parameters including temperature, pH, dissolved oxygen, and gas supply
- Collect in-process samples for routine analysis
Cryopreservation & Cell Banking
- Harvest cultures for long-term storage
- Prepare freezing suspensions using appropriate cryoprotectants
- Aliquot into cryovials and perform controlled freezing steps
- Maintain cryogenic storage inventory and records
Documentation & Compliance
- Maintain accurate batch records and laboratory documentation
- Record culture observations, process steps, and test results
- Follow established SOPs and aseptic handling procedures
- Adhere to safety and biosafety requirements
Requirements
- Bachelor's degree in Cell Biology, Molecular Biology, Bioengineering, Biotechnology, or related discipline required
- MS preferred
- Extensive research and development experience in cell culture, cell line development, or bioprocess engineering
- Industry experience in biologics, cell therapy, or related manufacturing environments
- Aseptic technique and sterile handling
- Mammalian cell culture fundamentals
- Laboratory safety and biosafety practices
- Basic bioreactor operations
- Microscopy and culture assessment
- Accurate record keeping and documentation
- SAP ERP Systems
Company overview
Waters Corporation is a global leader in analytical instruments, separations technologies, and software solutions serving the life, materials, food, and environmental sciences industries. Founded in 1958 and headquartered in Milford, Massachusetts, the company specializes in high-performance liquid chromatography (HPLC), ultra-performance liquid chromatography (UPLC), mass spectrometry systems, and laboratory informatics software. With approximately 7,600 employees worldwide, Waters provides critical analytical tools that enable pharmaceutical companies, research institutions, and quality control laboratories to ensure drug safety, food purity, and environmental monitoring. The company's innovative technologies support scientific discovery, product development, and regulatory compliance across multiple sectors, making it an essential partner for laboratory-dependent organizations seeking to advance scientific understanding and improve human health through precise measurement and analysis.