Senior Site Reliability Engineer
Formation Bio
Summary
As a Senior Site Reliability Engineer at Formation Bio, you will build and operate the infrastructure, delivery systems, and operational practices that allow our engineering organization to ship reliable software quickly and safely. You will work across cloud infrastructure, developer platforms, observability, and production workloads, including product applications, internal tools, data systems, and ML and AI workloads, taking problems from initial diagnosis through implementation and production adoption.
Job description
About the Position
As a Senior Site Reliability Engineer at Formation Bio, you will build and operate the infrastructure, delivery systems, and operational practices that allow our engineering organization to ship reliable software quickly and safely. You will work across cloud infrastructure, developer platforms, observability, and production workloads, including product applications, internal tools, data systems, and ML and AI workloads, taking problems from initial diagnosis through implementation and production adoption.
Formation Bio is an AI-native engineering organization. You will use modern AI tools, including agentic coding systems, as part of your daily engineering practice while applying the judgment needed to validate their output and operate reliable production systems. You will partner closely with Product Engineering, Data Engineering, and Data Science to design, build, and develop the infrastructure and operational platform that supports product software, data systems, and ML and AI workloads.
Responsibilities
- Own the infrastructure and operational platform for shared engineering workloads, including compute, runtime environments, orchestration, deployment, observability, access controls, and reliability.
- Build and operate secure, observable, reliable infrastructure for product applications, containerized services, internal tools, data systems, ML pipelines, inference, and agentic software.
- Research, develop, and maintain core AWS infrastructure and additional cloud outposts for services across development, staging, and production, including compute, networking, databases, load balancers, and secrets management.
- Create, review, maintain, and optimize infrastructure as code, CI/CD pipelines, and reusable platform patterns.
- Establish strong operational practices, including SLOs, monitoring, alerting, runbooks, incident response, advanced diagnostics, root cause analysis, and post-incident follow-through.
- Work with Product Engineering, Data Engineering, and Data Science to evaluate, negotiate, and implement architecture and infrastructure for product software, data systems, model training, and inference based on functional requirements.
- Use AI tools to accelerate infrastructure development, investigate incidents, improve documentation, build automation, and make operational improvements while validating their output.
- Participate in the support rotation and incident response.
- Maintain a strong bias for automation, the patience for ClickOps, and the experience to know when each is appropriate.
- Write and review requirements, design documents, and operating procedures.
- Share knowledge and mentor engineers on infrastructure and SRE fundamentals.
About You
- 5+ years of relevant experience in Site Reliability Engineering, infrastructure, systems, DevOps, or a similar discipline.
- Production experience operating cloud infrastructure and distributed systems, with strong operational and reliability judgment.
- Experience with advanced diagnostics, incident response, root cause analysis, observability, and automation.
- Experience with AWS and Snowflake.
- Experience with Azure, GCP, and/or Vercel is a plus.
- Working experience with Docker, GitHub, Kubernetes, Python, Terraform or OpenTofu, and virtual networking.
- Terragrunt is a plus.
- Experience supporting production ML or AI workloads, MLOps infrastructure, workflow orchestration, model serving, or a related platform is a plus.
- Strong SRE and infrastructure fundamentals are the core requirements.
- Experience managing shared COTS and FOSS software applications in addition to our internal software and tools.
- Daily fluency with AI tools, including LLMs and agentic coding systems, paired with strong engineering judgment and a high bar for validation.
- Exceptional collaboration and communication skills across engineering, Data Science, Data Engineering, Security, and non-technical partners.
- Experience operating infrastructure in a regulated or validated environment is a plus.
Requirements
- 5+ years of relevant experience in Site Reliability Engineering, infrastructure, systems, DevOps, or a similar discipline
- Production experience operating cloud infrastructure and distributed systems
- Experience with advanced diagnostics, incident response, root cause analysis, observability, and automation
- Experience with AWS and Snowflake
- Working experience with Docker, GitHub, Kubernetes, Python, Terraform or OpenTofu, and virtual networking
- Strong SRE and infrastructure fundamentals
- Experience managing shared COTS and FOSS software applications
- Daily fluency with AI tools, including LLMs and agentic coding systems
- Exceptional collaboration and communication skills
- Experience with Azure, GCP, and/or Vercel is a plus
- Terragrunt is a plus
- Experience supporting production ML or AI workloads, MLOps infrastructure, workflow orchestration, model serving, or a related platform is a plus
- Experience operating infrastructure in a regulated or validated environment is a plus
Benefits
- Equity
- Comprehensive benefits
- Generous perks
Company overview
Formation Bio is an AI-native pharmaceutical company revolutionizing drug development through technology-driven innovation. Founded in 2013 and headquartered in New York City with additional hubs in Boston, San Francisco Bay Area, and North Carolina's Research Triangle, the company focuses on acquiring clinical-stage drug assets from pharmaceutical and biotech companies to develop them faster and more efficiently. Formation Bio has built proprietary AI platforms that optimize critical aspects of clinical drug development, enabling more efficient trial design, faster trial completion, and higher quality trial data. The company's mission is to bring new treatments to patients faster by applying first-principles thinking and data-driven iteration to the traditionally slow and complex drug development process. With a team of 51-200 employees combining expertise from both technology and pharmaceutical backgrounds, Formation Bio has raised significant funding from prominent investors including Andreessen Horowitz, Sequoia Capital, and Thrive Capital. The company's innovative approach has earned recognition including the 2025 CNBC Disruptor 50 and 2025 Fierce 15 awards.