Senior Software Engineer
Natera
Summary
As a Senior Software Engineer at Natera, you will own the architecture, quality, and reliability of the systems you build. You bring deep expertise in designing scalable clinical software within a regulated healthcare environment, architecting systems with observability and testability at their core. This role is ideal for engineers with a strong automation and quality engineering foundation who are looking to expand their full-stack or backend software development scope.
Job description
Position Summary
As a Senior Software Engineer at Natera, you will own the architecture, quality, and reliability of the systems you build. You bring deep expertise in designing scalable clinical software within a regulated healthcare environment, architecting systems with observability and testability at their core. This role is ideal for engineers with a strong automation and quality engineering foundation who are looking to expand their full-stack or backend software development scope.
Working alongside Engineering, Product Management, and Design, you will build new features and user experiences while establishing the automated quality practices that empower the team to ship rapidly and safely.
Primary Responsibilities
- Design, build, and maintain production software systems and scalable, well-tested APIs from technical specifications.
- Own the quality lifecycle of the features you develop, spanning unit, integration, and system-level validation.
- Architect and maintain robust test automation frameworks, leveraging modern AI-assisted development and testing tools to accelerate engineering velocity and test coverage.
- Partner with the architecture team on system design to ensure reliability, observability, and testability are built in from the ground up.
- Embed automated test suites directly into CI/CD pipelines to support continuous build, test, and deployment cycles.
- Conduct thorough code reviews focused on functionality, maintainability, and test coverage while mentoring peers on software design and quality best practices.
- Collaborate with Product Managers to translate product designs into comprehensive verification and validation strategies, and clearly document and triage discovered issues with affected teams.
- Maintain current status on all required Natera compliance and regulatory training.
Qualifications
- Bachelor's degree in Computer Science, a related technical field, or equivalent practical experience.
- 7+ years of experience across software development, test automation, and quality engineering.
- Proven track record building and maintaining production applications and automation frameworks in Java and Python.
- Hands-on experience designing microservices and scalable cloud-native applications, preferably on AWS.
- Deep familiarity with the full software development lifecycle (SDLC), with an emphasis on shifting quality left into every phase.
Knowledge, Skills, and Abilities
- Strong Object-Oriented Programming (OOP) fundamentals in Java and Python.
- Proficiency with modern testing frameworks and libraries such as Playwright, Selenium, JUnit, and TestNG.
- Experience with REST API design and testing, relational databases, and SQL (PostgreSQL preferred).
- Familiarity with Docker/containerization, CI/CD pipeline configuration, and core AWS services (e.g., SQS, S3, SNS, MSK).
- Strong analytical and debugging skills with a keen eye for system dependencies and integration points, paired with clear cross-team communication.
Requirements
- Bachelor's degree in Computer Science, a related technical field, or equivalent practical experience
- 7+ years of experience across software development, test automation, and quality engineering
- Proven track record building and maintaining production applications and automation frameworks in Java and Python
- Hands-on experience designing microservices and scalable cloud-native applications, preferably on AWS
- Deep familiarity with the full software development lifecycle (SDLC)
- Strong Object-Oriented Programming (OOP) fundamentals in Java and Python
- Proficiency with modern testing frameworks and libraries such as Playwright, Selenium, JUnit, and TestNG
- Experience with REST API design and testing, relational databases, and SQL (PostgreSQL preferred)
- Familiarity with Docker/containerization, CI/CD pipeline configuration, and core AWS services (e.g., SQS, S3, SNS, MSK)
- Strong analytical and debugging skills with a keen eye for system dependencies and integration points
- Clear cross-team communication
Benefits
- Medical, Dental & Vision
- Life & Disability Insurance
- Free Genetic Testing
- Fertility Care Benefits
- Pregnancy & Baby Bonding Leave
- 401(k) Benefits
- Commuter Benefits
- Employee Referral Program
Company overview
Natera is a global leader in cell-free DNA (cfDNA) testing, specializing in molecular diagnostics for oncology, women's health, and organ health. Founded in 2004 and headquartered in Austin, Texas, the company has developed a cutting-edge cfDNA technology platform that combines novel molecular biology techniques with bioinformatics software and artificial intelligence. Natera's proprietary technology enables detection down to a single molecule in a tube of blood, making it possible to provide highly accurate genetic testing services. The company's flagship products include Signatera, a personalized circulating tumor DNA test for cancer monitoring; Panorama, a non-invasive prenatal test for chromosomal abnormalities; and Prospera, a transplant rejection assessment test. With over 4,400 employees and operations in CLIA-certified, CAP-accredited laboratories in Austin and San Carlos, California, Natera has processed more than 12 million tests and validated its technology through over 300 peer-reviewed publications. The company went public in 2015 and continues to innovate in precision medicine, aiming to make personalized genetic testing part of standard healthcare to enable earlier interventions and improved patient outcomes.