Software Engineer, Automation and Control
Culture Biosciences
Summary
We're looking for a Software Engineer who has experience in automation and controls to design, build, and maintain automation systems for our Bioreactor and Bioprocessing business. This person is comfortable with physical systems, has a deep understanding of control loop theory, and comes with a strong focus in controls, closed-loop system behavior, and PID-based control strategies. When a temperature control starts to oscillate, you can dive in, look at the traces, have a working theory of where the feedback loop went wrong, and come up with solutions to compensate and add margin to the design.
Job description
The Opportunity
We're looking for a Software Engineer who has experience in automation and controls to design, build, and maintain automation systems for our Bioreactor and Bioprocessing business. This person is comfortable with physical systems, has a deep understanding of control loop theory, and comes with a strong focus in controls, closed-loop system behavior, and PID-based control strategies. When a temperature control starts to oscillate, you can dive in, look at the traces, have a working theory of where the feedback loop went wrong, and come up with solutions to compensate and add margin to the design.
The role is more than just PID tuning. You will own everything from the interface of our Cloud software through the low-level control of a physical device (from Ethernet to USB). This role will work across software, hardware, and systems teams to develop reliable automation solutions for complex physical systems, improve process performance, and enable scalable, repeatable operation. Our software controls physical processes that run for days at a time, where failures can ruin an expensive experiment.
What You'll Do
- Tune and troubleshoot control loops in real-world environments, including diagnosing oscillation, lag, overshoot, and instability. Improve automation reliability through monitoring, logging, fault detection, and recovery mechanisms.
- Evolve our AsyncAPI hardware interface so higher-level automation and AI systems can safely interact with physical equipment, with explicit permissions, validation, and fail-safe behavior.
- Continuously improve the tuning and failure modes of our existing control loops and develop and optimize new feedback control systems, including PID control loops, for stability, performance, and robustness.
- Build software interfaces for sensors, actuators, embedded controllers, and higher-level orchestration systems.
- Partner with mechanical, electrical, process, and software engineers to translate system requirements into reliable control implementations.
- Learn about biotechnology and bioprocess development
About You
- 4+ years of industry experience including 2+ years developing software.
- Working knowledge of sensors, actuators, and data acquisition, and the ways they fail.
- Strong understanding of classical control theory, especially PID control, feedback loops, stability, response tuning, and disturbance rejection.
- Strong working relationship with scientists and the ability to translate process requirements into control logic.
- You care about technical rigor: testing assumptions, validating behavior against data, and understanding failure modes rather than stopping at "it works."
- Strong systems thinking and ability to work across hardware and software boundaries.
- You're kind, curious, and enjoy learning new things.
Preferred Skills
- Experience in robotics, manufacturing automation, biotech automation, or other complex electromechanical systems.
- Professional software engineering experience, including CI and automated testing.
- AWS, Docker, infrastructure as code, or connected edge devices.
- Exposure to regulated environments (GLP/GMP, ISO).
- Familiarity with sampling, filtering, sensor noise, and actuator constraints.
Location & Schedule
- This position is based in our South San Francisco office and will be required to be on site 3 days a week Monday through Friday.
Requirements
- 4+ years of industry experience including 2+ years developing software.
- Working knowledge of sensors, actuators, and data acquisition, and the ways they fail.
- Strong understanding of classical control theory, especially PID control, feedback loops, stability, response tuning, and disturbance rejection.
- Strong working relationship with scientists and the ability to translate process requirements into control logic.
- You care about technical rigor: testing assumptions, validating behavior against data, and understanding failure modes rather than stopping at "it works."
- Strong systems thinking and ability to work across hardware and software boundaries.
- You're kind, curious, and enjoy learning new things.
Benefits
- Competitive salary and equity compensation
- Medical, Dental, Vision, and Life insurance
- Medical and Dependent Care FSA
- 401(k) plan with company match
- Responsible Time Off
- 11 paid company holidays
- Week-long winter break
- 12 weeks parental leave
Company overview
Culture Biosciences is a pioneering biotechnology company that has revolutionized bioprocess development through its innovative cloud-based bioreactor platform. Founded in 2016 and headquartered in South San Francisco, California, the company operates as a 'bioreactor lab in the cloud,' enabling scientists to accelerate bioprocess development with high-throughput bioreactor services. Culture Biosciences' integrated platform combines automated bioreactors, robotic sample handling, and cloud data monitoring to provide comprehensive bioprocessing solutions. Customers can design experiments remotely while Culture executes them using their proprietary 250mL and 5L bioreactors, with real-time monitoring and data analysis available through their online dashboard. The company serves biotech companies working on therapeutics, materials, fuels, and foods, helping them quickly run experiments and develop manufacturing processes to bring products to market faster. With over 20,000 bioreactor runs completed and more than 70 customers served, Culture Biosciences has established itself as a leader in cloud-native bioprocessing technology, offering services including strain screening, media optimization, process characterization, and bioprocess modeling. Their recent innovations include the Stratyx™ 250 cloud-integrated mobile bioreactor system, which further enhances remote process control and automation capabilities.