Sr Assoc Scientist

When & where

• Shift Requirements: Full-time
• Location: On-site in Tarrytown, NY

What you'll do

• Design and independently execute phase-appropriate formulation development studies, such as formulation screening, stability, and compatibility studies, to support drug product development for early- and late-stage development programs
• Conduct pre-formulation studies for monoclonal antibodies, bioconjugates, and peptides, using various biophysical and biochemical techniques to identify critical quality attributes for formulation and drug product development
• Characterize drug product formulation to support process development and manufacturing of clinical drug substances and drug products
• Document findings and lab records in electronic laboratory notebook, following organizational best practices and policies
• Contribute to formulation development technical reports to provide insights into process development and manufacturing of clinical drug substances and drug products
• Participate in meetings and present study results in cross-functional team meetings or department meetings
• Author protocols and technical documents for internal use, and support regulatory filings
• Take part in general laboratory and instrument maintenance

The environment and physical rhythms of this role

• This is a laboratory environment requiring the ability to design and execute experiments, as well as interpret, document, and communicate results with minimal supervision.
• Strong ability to prioritize and manage multiple tasks effectively, while remaining highly organized, detail-oriented, self-motivated, and an effective team player, is required.

Must-haves

• B.S. or M.S. degree in Pharmaceutical Sciences, Chemistry, Biochemistry, Biophysics, Biomedical Engineering, Analytical Chemistry, Chemical Engineering, or a related discipline, with at least 3 years of industrial experience
• Ability to design and execute experiments, and interpret, document, and communicate results with minimal supervision
• Ability to take direction and guidance for data-driven decision making, priority setting, and technical problem solving
• Ability to generate and organize data figures and data tables in a clear and insightful way
• Excellent oral and written communication skills

Preferred / nice-to-haves

• Strong technical knowledge base and relevant experience with protein/peptide chemistry, biophysical/biochemical characterization of proteins, bioanalytical method development, and biomolecule product development
• Hands-on experience with biochemical and biophysical techniques for protein characterization, including chromatography (SEC, IEX, RP), viscosity, gel electrophoresis (CE-SDS, MCE, cIEF, iCE), particle size (DLS, HIAC, MFI), spectroscopy (UV-Vis, CD, AUC, fluorescence), and thermostability characterization (DSC, DSF)