Sr Associate Scientist, Biology

The candidate will demonstrate scientific rigor, strong experimental execution, and the ability to independently generate, interpret, and communicate high-quality data. The successful candidate will be proficient in developing and executing in vitro assays to support target validation, mechanism-of-action studies, lead discovery, and candidate characterization.

Experience with primary immune cells, reporter assays, cytotoxicity assays, and engineered cellular systems is highly desirable. Exposure to in vivo pharmacology studies, including preclinical mouse models, tissue processing, and translational assessment, is preferred.

Key Responsibilities

• Develop cell-based assays using primary and engineered mammalian cells to evaluate and characterize drug candidates.
• Design and execute experiments to screen and characterize preclinical and clinical-stage candidates within our engager pipeline.
• Perform mammalian cell culture, gene engineering, and stable cell line generation to support discovery and mechanistic studies.
• Isolate and characterize primary immune cells using flow cytometry and other cellular analysis techniques.
• Conduct a range of cell-based functional assays, including reporter, proliferation, and cytotoxicity assays.
• Collaborate with cross-functional teams across diverse therapeutic areas, with a primary focus on immuno-oncology/engagers.
• Apply innovative experimental approaches, learn new technologies, and contribute to multiple projects in a fast-paced research environment.
• Analyze and interpret experimental data and communicate findings through team discussions and cross-functional presentations.
• Contribute to the design, execution, and interpretation of in vivo studies; hands-on experience with preclinical mouse models, dosing, tissue collection, and pharmacology studies is highly desirable.

Basic Qualifications

5+ Years with BS OR 3+ Years with MS

Preferred Qualifications

• Bachelor's degree in Immunology, Biology, Biochemistry, Pharmacology, Molecular Biology, Oncology, Pharmaceutical Sciences, or a related scientific discipline with 5+ years of relevant industry experience, OR Master’s degree in Immunology, Biology, Biochemistry, Pharmacology, Molecular Biology, Oncology, Pharmaceutical Sciences, or a related scientific discipline with 3+ years of relevant industry experience.
• Industry experience supporting drug discovery, translational research, assay development, screening sciences, pharmacology, bioanalysis, or a related scientific discipline.
• Knowledge of immunology, protein biology, and mammalian cell culture techniques; hands-on bench research experience preferred
• Ability to multitask experiments and data analysis across diverse projects
• Experience working independently as well as within a collaborative team environment
• Ability to communicate effectively within a large team
• Excellent adaptability and flexibility, with great attention to detail and outstanding organizational skills
• A background in in-vitro T cell characterization (functional and antigen-binding assays) is a plus
• Experience with cell-based assays, immunoassays (flow cytometry or plate reader-based) and basic molecular biology techniques is also a plus
• High-throughput screening experience and familiarity with liquid handlers are beneficial