Summary

As a Senior Associate Scientist in the Early Bioprocess Development within Pfizer Vaccine Research and Development, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will join a large team of Scientists focused on conjugation process development for manufacturing carbohydrate-based conjugate vaccines. Primary duties include supporting the development and optimization of conjugation methods, purification, and analysis of intermediates and glycoconjugates using chemical and chromatographic methods. The individual will become a key contributor towards supporting the early development and scale up of glycoconjugate vaccines. Careful documentation of work and presentation of data is required. All work is to be done in a compliant manner according to SOP guidelines and cGMP/GLP regulations, where applicable.

Job description

Role Summary

As a Senior Associate Scientist in the Early Bioprocess Development within Pfizer Vaccine Research and Development, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will join a large team of Scientists focused on conjugation process development for manufacturing carbohydrate-based conjugate vaccines. Primary duties include supporting the development and optimization of conjugation methods, purification, and analysis of intermediates and glycoconjugates using chemical and chromatographic methods. The individual will become a key contributor towards supporting the early development and scale up of glycoconjugate vaccines. Careful documentation of work and presentation of data is required. All work is to be done in a compliant manner according to SOP guidelines and cGMP/GLP regulations, where applicable.

Role Responsibilities

Support the development, optimization and scale-up of glycoconjugate vaccine process development.
In process analysis of glycoconjugates and intermediates.
Continuously evaluate each process and technique to determine if it is robust, appropriate, and scalable. If an operation has shortcomings or can be improved, propose solution in discussion with other group members to advance objectives.
Collaborate with colleagues within Vaccine Research and Development organization including Early Bioprocess fermentation, purification, analytical and formulation development groups.
Participate in the technology transfer of developed process to clinical manufacturing site, both internally and externally, and provide the technical support as needed.
Fully document laboratory experiments in electronic notebook in a timely and compliant manner and prepare technical reports as needed.
Perform other duties as assigned.

Qualifications

Must have BS degree in Chemistry/Biochemistry or related discipline with 3 to 6 years laboratory experience or MS degree in Chemistry/Organic Chemistry or related discipline with 0 to 4 years of experience.
Strong background in organic chemistry is required.
Knowledge and ability to operate and maintain relevant instruments, resolve technical problems related to instruments, and execution of analytical methods.
Independently analyze and provide conclusions regarding experimental data generated.
Strong verbal and written communication skills are required.
Experience with documentation of laboratory notebook in an electronic format.

Nice To Have

Experience in carbohydrate chemistry
Hands on experience with various analytical techniques such as HPLC, MALS, UV-Vis, NMR, and other routine lab instruments.
Proficiency with personal computers including word processing, spreadsheets, PowerPoint, and relevant scientific software

Requirements

BS degree in Chemistry/Biochemistry or related discipline with 3 to 6 years laboratory experience or MS degree in Chemistry/Organic Chemistry or related discipline with 0 to 4 years of experience
Strong background in organic chemistry
Knowledge and ability to operate and maintain relevant instruments, resolve technical problems related to instruments, and execution of analytical methods
Independently analyze and provide conclusions regarding experimental data generated
Strong verbal and written communication skills
Experience with documentation of laboratory notebook in an electronic format

Benefits

401(k) Matching
Retirement Savings Contribution
Paid Vacation
Paid Holidays
Paid Personal Days
Paid Caregiver Leave
Paid Parental Leave
Paid Medical Leave
Medical Insurance
Prescription Drug Coverage
Dental Insurance
Vision Insurance
Relocation Support

Company overview

Pfizer Inc. is an American multinational pharmaceutical and biotechnology corporation headquartered in New York City, founded in 1849 by German entrepreneurs Charles Pfizer and Charles F. Erhart. As one of the world's largest pharmaceutical companies, Pfizer develops and produces medications and vaccines across multiple therapeutic areas including immunology, oncology, cardiology, endocrinology, and neurology. The company is renowned for breakthrough drugs such as Lipitor, Viagra, and more recently, the Pfizer-BioNTech COVID-19 vaccine. With approximately 81,000 employees globally and operations in about 200 countries, Pfizer maintains 37 manufacturing sites worldwide. The company's current strategic focus includes oncology, rare diseases, and innovative vaccine development, while implementing significant cost-saving initiatives. Pfizer continues to advance its research pipeline with over 100 projects and maintains a strong commitment to scientific innovation and global healthcare access.