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Sr. Manager, Bioinformatics

Illumina

San Diego, CARemotePosted 11 days ago$170,600 - $255,800
Full TimeSenior LevelBioinformatics & Data ScienceGenomics
Original posting ↗

Summary

The Sr. Manager, Bioinformatics will lead a team of bioinformatics scientists supporting Illumina's Clinical Genomics portfolio, including oncology, reproductive health, and regulated clinical sequencing products. This leader will oversee bioinformatics activities supporting assay development, software releases, regulatory submissions, and product commercialization. The role will partner closely with cross-functional teams to deliver high-quality bioinformatics solutions that support product development and customer success.

Job description

Responsibilities

  • Lead, mentor, and develop a team of bioinformatics scientists while fostering a culture of collaboration, innovation, and technical excellence.
  • Manage bioinformatics activities supporting Clinical Genomics product development, commercialization, and lifecycle management, including portfolio prioritization, resource allocation, and risk management across multiple programs.
  • Oversee development, validation, and deployment of analytical methods and bioinformatics workflows that support customer-facing software, assays, and regulated products.
  • Collaborate across R&D, Software Engineering, Biostatistics, Regulatory, Quality, Product Management, and Commercial teams to achieve program objectives and business goals.
  • Partner with customers, commercial teams, and external collaborators to support product adoption, provide bioinformatics expertise, troubleshoot complex technical challenges, and gather feedback to improve products and workflows.
  • Drive evaluation and adoption of new analytical approaches, technologies, and scalable bioinformatics solutions that advance product capabilities, operational efficiency, and customer value.

Requirements

  • Typically requires a Bachelor's degree and a minimum of 12 years of related experience, with 3-6 years of Management experience.
  • PhD in Bioinformatics, Computational Biology, Computer Science, Statistics, Genomics, or related scientific discipline, with 8+ years of relevant experience preferred
  • Demonstrated leadership experience managing bioinformatics teams and complex cross-functional programs.
  • Experience supporting regulated products, including IVD, CDx, FDA, IVDR, or similar regulatory frameworks.
  • Strong understanding of next-generation sequencing, genomics data analysis, and bioinformatics pipeline development.
  • Experience supporting customers, commercial teams, or external collaborators in the deployment and adoption of genomics products and bioinformatics solutions.
  • Proficiency with bioinformatics software development and analysis tools, including Python, R, and Linux-based environments.
  • Excellent communication, stakeholder management, and organizational leadership skills.

Requirements

  • Bachelor's degree and a minimum of 12 years of related experience, with 3-6 years of Management experience
  • PhD in Bioinformatics, Computational Biology, Computer Science, Statistics, Genomics, or related scientific discipline, with 8+ years of relevant experience preferred
  • Demonstrated leadership experience managing bioinformatics teams and complex cross-functional programs
  • Experience supporting regulated products, including IVD, CDx, FDA, IVDR, or similar regulatory frameworks
  • Strong understanding of next-generation sequencing, genomics data analysis, and bioinformatics pipeline development
  • Experience supporting customers, commercial teams, or external collaborators in the deployment and adoption of genomics products and bioinformatics solutions
  • Proficiency with bioinformatics software development and analysis tools, including Python, R, and Linux-based environments
  • Excellent communication, stakeholder management, and organizational leadership skills

Benefits

  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • Retirement Benefits
  • Paid Time Off
  • Family Planning
  • Genomics Sequencing Access
  • Variable Cash Programs
  • Equity

Company overview

Illumina is a global leader in genomics technology, founded in 1998 and headquartered in San Diego, California. As a pioneering biotechnology company, Illumina specializes in developing, manufacturing, and marketing integrated systems for genetic analysis, with a primary focus on DNA sequencing and array-based technologies. The company's mission is to improve human health by unlocking the power of the genome, serving customers across research, clinical, and applied markets worldwide. Illumina's innovative platforms, including the NovaSeq, HiSeq, MiSeq, and NextSeq series, have revolutionized genomic research and clinical applications, enabling breakthroughs in personalized medicine, disease research, and drug development. With over 9,000 employees across 27 countries, Illumina has established itself as the dominant force in next-generation sequencing, processing more than 90% of all DNA sequencing data globally. The company's technologies support diverse applications from cancer research and rare disease diagnosis to agricultural genomics and infectious disease surveillance, making genomic insights accessible to researchers and clinicians worldwide.

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