Sr. Scientist, Translational Research
Triveni Bio
Summary
Triveni Bio is seeking an experienced Scientist to join our Biology and Translational Research team. In this role, you will lead preclinical pharmacology studies and downstream analyses to advance novel therapeutics. The successful candidate will work with Triveni's team to test novel biologic drug candidates, delineate their mechanism of action, and address biological questions across multiple indications.
Job description
Summary
Triveni Bio is seeking an experienced Scientist to join our Biology and Translational Research team. In this role, you will lead preclinical pharmacology studies and downstream analyses to advance novel therapeutics. The successful candidate will work with Triveni's team to test novel biologic drug candidates, delineate their mechanism of action, and address biological questions across multiple indications.
Responsibilities
- Play a key role in the development of new biologic drugs for immunotherapy. Independently propose, plan and perform in vivo and in vitro studies to characterize the company's drug candidates and their mechanism of action.
- Design, develop, troubleshoot and establish in vivo models and in vitro assays to evaluate the biological efficacy of novel therapeutic agents.
- Manage external research activities with CROs and academic collaborators, ensuring timelines, deliverables, and data quality.
- Present research findings at internal meetings and contribute to external scientific discussions; prepare scientific reports and summaries.
- Provide technical guidance, mentorship, and troubleshooting support to junior associates.
Experience & Qualifications
- Ph.D. in molecular biology or a related discipline, with 5+ years of relevant experience in academia, the pharmaceutical industry, biotechnology, or a combination thereof.
- Strong background in immunology and inflammation, experience in dermatology is a plus.
- Hands-on expertise in preclinical in vivo pharmacology and animal disease models.
- Demonstrated expertise in a range of functional assays, including ELISA, qRT-PCR, Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF).
- Proven track record of successfully managing CROs, external vendors, and academic partnerships.
- Proven ability to independently manage projects and work effectively with cross functional teams.
Requirements
- Ph.D. in molecular biology or a related discipline
- 5+ years of relevant experience in academia, pharmaceutical industry, or biotechnology
- Strong background in immunology and inflammation
- Hands-on expertise in preclinical in vivo pharmacology and animal disease models
- Expertise in functional assays including ELISA, qRT-PCR, Western blotting, IHC, and IF
- Proven track record managing CROs, external vendors, and academic partnerships
- Proven ability to independently manage projects and work with cross-functional teams
Benefits
- Target Bonus
- Equity
- Comprehensive Benefits Package
Company overview
Triveni Bio is a clinical-stage biotechnology company pioneering a genetics-informed precision medicine approach to develop functional antibodies for the treatment of immunological and inflammatory (I&I) disorders. Founded in 2019 and headquartered in Watertown, Massachusetts, the company leverages advanced antibody engineering to build first-in-class therapeutics that aim to redefine treatment paradigms for complex diseases. Triveni's lead asset, TRIV-509, is a dual-specific monoclonal antibody targeting kallikreins 5 and 7 for the treatment of atopic dermatitis, currently in Phase 2 clinical trials. The company's approach establishes proof-of-concept at the earliest stages of drug development by combining human genetics insights with mechanistic biology to identify novel targets and develop precision medicines. Triveni Bio has raised significant funding, including a $115 million Series B round in 2024, and has been recognized as a Fierce 15 biotech company for its innovative approach to addressing unmet medical needs in dermatology and immunology.