Sr Technical Product Owner

About the Role

At Twist Bioscience, we're scaling the digital systems that power our synthetic DNA platform and enable innovation across our commercial, scientific, and operational teams. We're seeking a Senior Technical Product Owner to lead cross-functional system projects, someone who can dive deep into the details while helping improve how we work. In this role, you will own hands-on work across requirements gathering, documentation, and testing for high-impact system initiatives. This role sits at the intersection of product, engineering, and business.

What You will do

You will serve as the primary business-facing partner on system initiatives, owning the functional definition of what needs to be built and partnering closely with engineering and project management, who own technical design, delivery sequencing, and timelines.

Requirements and Solution definition

• Lead requirements intake and clarification with business stakeholders across functions (e.g., Product, Marketing, Sales Operations, Finance, Customer Support, and R&D).
• Define and document functional requirements, business rules, edge cases, and acceptance criteria, including impacted existing logic, constraints, and exceptions, and translate them into epics and user stories ready for development and QA.
• Identify impacted process areas, systems, and dependencies end to end (e.g., product setup, pricing, quoting, order intake, manufacturing, fulfillment, and invoicing), along with the SMEs and stakeholders within each.
• Drive alignment with cross-system partners and SMEs to ensure requirements are complete and consistent across integrated systems and address emerging business needs.
• Ensure requirements and solutions are compliant and audit-ready (e.g., SOX, ISO), partnering with Finance, Quality and other internal stakeholders.
• Demonstrate strong customer empathy and advocate for customer needs throughout the product development process.

Delivery partnership and communication

• Provide development leads, architects, and project managers with the full end-to-end context and scope of each initiative, and lead functional grooming sessions.
• Partner with project management, scrum masters, developers, architecture, and SWQA through design, build, testing, and delivery, clarifying requirements and surfacing risks, gaps, and dependencies early.
• Communicate proactively and consistently with business stakeholders on scope, status, risks, and dependencies throughout each initiative.
• Influence scope tradeoffs and solution options by bringing business and cross-system context to technical discussions.

Testing, launch, and stabilization

• Plan and lead end-to-end user acceptance testing across multiple systems: kick off with testers, provide context and demos, support issue logging and defect clarification, and obtain stakeholder sign-off before go-live.
• Support release, hypercare, and post-launch stabilization, providing business context to help assess the criticality of issues.
• Stay informed on production issues and contribute business and system context to their resolution.

Continuous improvement

• Share feedback and ideas to continuously improve how the team runs projects, gathers requirements, and tests, including intake playbooks, documentation standards, and testing practices.
• Look for opportunities to leverage AI tools to work more efficiently, such as in requirements documentation, analysis, and testing.