Summary

The Drug Discovery team is looking for a Senior Research Associate I, Compound Management to join our group. In this role, you will help power the discovery of new medicines by ensuring scientists across the organization have access to the high-quality compounds and samples needed to advance research programs. Your work will directly enable scientists to advance programs aimed at translating novel genetic insights into lifesaving medicines. You will partner closely with colleagues across Drug Discovery, including Chemistry, Biology, and other cross-functional teams, to manage compound inventory, support sample management workflows, and help maintain the efficient operation of our compound management capabilities.

Job description

The Position

The Drug Discovery team is looking for a Senior Research Associate I, Compound Management to join our group. In this role, you will help power the discovery of new medicines by ensuring scientists across the organization have access to the high-quality compounds and samples needed to advance research programs. Your work will directly enable scientists to advance programs aimed at translating novel genetic insights into lifesaving medicines. You will partner closely with colleagues across Drug Discovery, including Chemistry, Biology, and other cross-functional teams, to manage compound inventory, support sample management workflows, and help maintain the efficient operation of our compound management capabilities.

The Impact You'll Have

Manage the weighing, storage, maintenance, and distribution of compound inventories.
Responsible for the operation of automated laboratory equipment to support the processing of samples.
Proactively monitor the compound request queue and fulfill the requests in a timely manner.
Partner with Facilities Department for the shipping and tracking of compounds both locally and internationally to our collaborating CROs.
Routinely perform sample QC checks and analysis.
Coordinate with R&D operations, vendors, and CROs to procure, track, and process samples to support internal and external studies.
Assist in the development and implementation of workflows to support error-free high throughput compound processing.
Coordinate cross-departmentally for routine or ad hoc compound plating.
Maintain lab consumable inventory.

What We're Looking For

Minimum of a BS degree in Biological or Chemical Sciences with 3+ years of experience in small molecule compound handling and processing.
Experience with laboratory automation, specifically liquid handling platforms like Tecan EVO, Labcyte ECHO or similar.
Experience with troubleshooting and maintenance of instrumentation platforms and automated integrated systems.
Experience with optimizing compound processing workflows including knowledge and use of Mosaic is desired.
Innate attention to detail, organization skills, ability to multi-task and work across initiatives simultaneously under tight deadlines.
Effective communication skills and strong interpersonal skills to engage in cross-functional collaboration and teamwork.

Requirements

Minimum of a BS degree in Biological or Chemical Sciences
3+ years of experience in small molecule compound handling and processing
Experience with laboratory automation, specifically liquid handling platforms like Tecan EVO, Labcyte ECHO or similar
Experience with troubleshooting and maintenance of instrumentation platforms and automated integrated systems
Experience with optimizing compound processing workflows including knowledge and use of Mosaic is desired
Innate attention to detail, organization skills, ability to multi-task and work across initiatives simultaneously under tight deadlines
Effective communication skills and strong interpersonal skills to engage in cross-functional collaboration and teamwork

Benefits

Medical, Dental & Vision
Mental Health Offerings
Equity Incentive Plan
401(k) Matching
Holiday & PTO Policy
Annual Performance Bonus

Company overview

Maze Therapeutics is a clinical-stage biopharmaceutical company that leverages human genetics to develop precision medicines for common diseases with significant unmet medical needs. Founded in 2017 and headquartered in South San Francisco, California, the company has developed Maze Compass™, a proprietary platform that integrates genetic variant functionalization into therapeutic development. Maze focuses on renal, cardiovascular, metabolic diseases, and obesity, with a pipeline that includes MZE829 (an APOL1 inhibitor in Phase II trials for APOL1-mediated kidney disease), MZE782 (an SLC6A19 inhibitor in Phase I for chronic kidney disease), and MZE001 (a glycogen synthase 1 inhibitor for Pompe disease). The company employs approximately 125 professionals and operates with a strategy that includes independent development, pharmaceutical collaborations, and company formation. Maze's approach combines genetic insights with small molecule drug development to create targeted therapies for patient populations with limited treatment options.