Statistics Leader / Associate Director, Oncology Statistics
GSK
Summary
GSK Oncology is committed to discovering and developing new therapies with the potential to change the lives of patients with cancer. The Oncology Clinical Development Statistics group is seeking exceptionally talented Statisticians to provide end-to-end statistical leadership across oncology evidence generation—from early development through registration and lifecycle support—using innovative trial designs and modern statistical methods (including simulation, interim strategies, Bayesian approaches, and external/real-world data) to inform key development decisions.
Job description
Responsibilities
- Provide statistical leadership for oncology studies/indications, partnering with project and study teams to align strategy and execution
- Lead statistical strategy for study design, analysis, reporting, and interpretation, applying fit-for-purpose methods (e.g., simulation, interim strategies, Bayesian) to quantify uncertainty and inform decisions
- Author/review statistical sections of protocols, SAPs, clinical/regulatory documents, and presentations; communicate complex results clearly to non-statistical stakeholders
- Ensure high-quality, on-time deliverables and effective stakeholder management in a matrix environment
- Drive innovation in statistical methodology and data strategy, including appropriate use of external/real-world data to strengthen oncology evidence generation
- Build deep indication knowledge (e.g., regulatory expectations, competitor landscape) and influence asset strategy and regulatory submissions with rigorous statistical insight
- Represent Oncology Biostatistics externally as appropriate and may serve as project statistician for an oncology asset
Basic Qualifications
- PhD (preferred) or MS/MSc in Statistics (or related quantitative field) with at least 6 years post-degree experience for PhD holders, or equivalent experience for master's holders
- Three or more years of experience supporting Oncology Clinical development in pharmaceutical, biotech, or CRO settings
- Three or more years of experience in the delivery of fit-for-purpose statistical solutions
- Three or more years of experience coding in R and/or Python; working knowledge of SAS is a plus
Preferred Qualifications
- Hands-on expertise in statistical modeling and innovative methods (e.g., Bayesian approaches)
- Thorough knowledge of the drug development process including late-phase development, registration activities, and oncology regulatory expectations
- Familiarity with causal inference and/or AI/ML methods, and interest in applying these approaches (when appropriate) to clinical and/or real-world data
- Demonstrated ability to lead or make major contributions to department, organizational and/or industry-wide initiatives, through effective communication and influence
- Strong communication and stakeholder-management skills, with demonstrated ability to influence across functions in a matrix environment
- Highly organized, self-directed, and able to manage multiple priorities across projects
Requirements
- PhD (preferred) or MS/MSc in Statistics or related quantitative field
- At least 6 years post-degree experience for PhD holders, or equivalent experience for master's holders
- Three or more years of experience supporting Oncology Clinical development in pharmaceutical, biotech, or CRO settings
- Three or more years of experience in the delivery of fit-for-purpose statistical solutions
- Three or more years of experience coding in R and/or Python
- Working knowledge of SAS is a plus
- Hands-on expertise in statistical modeling and innovative methods (e.g., Bayesian approaches)
- Thorough knowledge of the drug development process including late-phase development, registration activities, and oncology regulatory expectations
- Familiarity with causal inference and/or AI/ML methods
- Strong communication and stakeholder-management skills
- Highly organized, self-directed, and able to manage multiple priorities
Benefits
- Health care
- Insurance benefits
- Retirement benefits
- Paid holidays
- Vacation
- Paid caregiver leave
- Paid parental leave
- Paid medical leave
- Annual bonus
- Share based long term incentive program
Company overview
GSK plc (formerly GlaxoSmithKline) is a British multinational pharmaceutical and biotechnology company headquartered in London, England. Founded in 2000 through the merger of Glaxo Wellcome and SmithKline Beecham, GSK has grown to become one of the world's leading healthcare companies with operations in over 150 countries. The company specializes in researching, developing, and manufacturing prescription medicines, vaccines, and consumer healthcare products. GSK's therapeutic areas include respiratory diseases, HIV/AIDS, oncology, immunology, and infectious diseases. The company is particularly renowned for its vaccine portfolio and has been at the forefront of developing treatments for major global health challenges. With approximately 70,000 employees worldwide, GSK maintains a strong commitment to scientific innovation and has a significant presence in key markets including the United States, Europe, and emerging economies. The company's mission is to unite science, technology, and talent to get ahead of disease together, aiming to positively impact the health of 2.5 billion people by the end of the decade.