Synthetic Chemist
Inductive Bio
Summary
We are seeking an accomplished Synthetic Chemist to help build the experimental chemistry capabilities behind Inductive's AI-forward drug discovery platform. This role combines medicinal chemistry strategy with hands-on synthesis expertise to design better compounds, solve challenging synthetic problems, and accelerate Design-Make-Test-Analyze workflows.
Job description
You'll play a key role in bridging computational design and experimental chemistry, bringing practical synthesis expertise to both the lab and the digital tools we're building.
This is an onsite role based in Boston, with regular visits to our local lab, reporting directly to our VP, Head of Medicinal Chemistry.
What You'll Do
- Apply your synthetic chemistry expertise to design, optimize, and troubleshoot synthetic routes across a diverse range of medicinal chemistry programs.
- Translate your practical knowledge into digital workflows that optimize synthetic routes, identify reaction conditions, streamline CRO communication, and track compound progress.
- Oversee synthesis activities with CRO partners, leveraging both your chemistry expertise and Inductive's technology to deliver high-quality compounds efficiently.
- Train and mentor laboratory technicians, ensuring reactions are executed safely, effectively, and reproducibly.
- Develop strategic approaches to compound and intermediate supply, including route optimization and scale-up to support ongoing medicinal chemistry exploration.
- Collaborate with medicinal chemists, computational scientists, and engineers to improve how compounds are designed, synthesized, and tested.
- Help shape a new approach to drug discovery by integrating hands-on chemistry expertise with AI-powered tools and workflows.
What We're Looking For
- A passion for advancing medicinal chemistry programs through practical, hands-on synthetic chemistry.
- Deep knowledge of modern synthetic methods, with a strong understanding of what works in practice at the bench.
- A track record of solving complex synthetic challenges across diverse chemotypes, reaction types, and scales.
- Experience mentoring junior chemists or technicians and sharing practical laboratory expertise.
- Strong communication and collaboration skills, with the ability to clearly articulate synthetic strategies and troubleshoot challenges with cross-functional teams.
- Demonstrated experience managing synthesis CROs, including both FTE-based teams and fee-for-service projects across multiple partners.
- Strategic thinking around material supply, including when to optimize routes, develop key intermediates, and scale synthesis to support program needs.
- Curiosity about emerging technologies and an interest in applying AI agents and digital tools to improve synthesis workflows.
Bonus Points
- Experience overseeing scale-up synthesis for in vivo toxicology studies or other late-stage drug discovery activities.
- Experience applying AI, automation, or digital tools to synthetic chemistry workflows.
- Experience working at the intersection of medicinal chemistry, computational chemistry, and experimental drug discovery.
Requirements
- Deep knowledge of modern synthetic methods
- Track record of solving complex synthetic challenges across diverse chemotypes, reaction types, and scales
- Experience mentoring junior chemists or technicians
- Strong communication and collaboration skills
- Demonstrated experience managing synthesis CROs, including FTE-based teams and fee-for-service projects
- Strategic thinking around material supply, route optimization, and scale-up
- Curiosity about emerging technologies and applying AI agents and digital tools
Benefits
- Equity-Based Compensation
- Healthcare Benefits
- Dental Insurance
- Vision Insurance
Company overview
Inductive Bio is an innovative biotechnology company that leverages advanced computational and experimental approaches to develop novel therapeutic solutions. The company's name suggests a focus on inductive reasoning methodologies applied to biological systems, potentially involving machine learning, data-driven discovery, and systematic analysis of biological pathways. While specific details about their pipeline are not readily available, companies with similar naming conventions typically operate in the emerging field of computational biology and AI-driven drug discovery. Inductive Bio likely employs sophisticated algorithms to identify promising drug targets, predict compound efficacy, and optimize therapeutic candidates through iterative learning processes. The company represents the convergence of data science and life sciences, aiming to accelerate the drug discovery timeline and improve success rates through evidence-based, systematic approaches to biological problem-solving. Their work may span various therapeutic areas including oncology, neurology, or metabolic disorders, utilizing proprietary platforms that integrate multi-omics data, phenotypic screening, and predictive modeling to uncover novel biological insights and therapeutic opportunities.