Technical Manager of Manufacturing Applications - USA Remote
Danaher Corporation
Summary
The Manager of Manufacturing Applications is responsible for ensuring compliant, reliable, and validated enterprise manufacturing platforms that support GxP-regulated operations across the organization. This position reports to the Director of Software Engineering and is part of the IT Manufacturing Applications team and is fully USA remote.
Job description
In this role, you will have the opportunity to:
- Own the end-to-end management of GxP-regulated manufacturing systems, including lifecycle planning, enhancements, upgrades, rationalization, and decommissioning.
- Ensure manufacturing systems operate in compliance with GxP regulations, internal quality standards, and inspection readiness expectations.
- Coordinate with the Validation team and govern change management for GxP systems, including validation planning, risk assessments, testing, documentation, change impact analysis, and ensuring changes are properly assessed, approved, tested, and deployed in alignment with validation and quality requirements.
- Partner closely with Quality, Manufacturing, and IT stakeholders to translate operational needs into compliant system capabilities and improvements.
- Oversee operational stability and performance of GxP systems, including incident management, root cause analysis, corrective and preventive actions (CAPAs), and continuous improvement.
- Manage vendors and service partners supporting GxP systems, ensuring compliance, performance, documentation, and service expectations are met.
- Maintain inspection-ready documentation, support internal and external audits and regulatory inspections, and coordinate training and user enablement to ensure proper system use and sustained compliance.
The essential requirements of the job include:
- Bachelor's degree in Information Technology, Engineering, Life Sciences, or a related discipline.
- At least 4 years of experience supporting or managing manufacturing IT systems in regulated environments, including experience with technically complex systems involving integrations, automation, or custom implementations, and at least 1 year of supervisory, management, technical lead, or team lead experience.
- Strong understanding of manufacturing systems (e.g., MES, LIMS, QMS, instruments related, or related manufacturing platforms).
- Experience operating within IT service management and quality governance processes, with hands on software development experience supporting system integrations, automation, or platform enhancements, using technologies such as C#, JavaScript/TypeScript, modern web frameworks (e.g. React), and API based integrations.
It would be a plus if you also possess previous experience in:
- Experience supporting global or multi site manufacturing environments.
- Exposure to manufacturing digital transformation initiatives.
- Demonstrated experience managing GxP-regulated systems, including validation support, compliance oversight, and change control in collaboration with Quality and Validation teams, while partnering with Manufacturing and Quality organizations to support compliant operations.
Requirements
- Bachelor's degree in Information Technology, Engineering, Life Sciences, or a related discipline.
- At least 4 years of experience supporting or managing manufacturing IT systems in regulated environments.
- Experience with technically complex systems involving integrations, automation, or custom implementations.
- At least 1 year of supervisory, management, technical lead, or team lead experience.
- Strong understanding of manufacturing systems (e.g., MES, LIMS, QMS, instruments related, or related manufacturing platforms).
- Experience operating within IT service management and quality governance processes.
- Hands-on software development experience supporting system integrations, automation, or platform enhancements.
- Experience with technologies such as C#, JavaScript/TypeScript, modern web frameworks (e.g. React), and API based integrations.
Benefits
- Health care program
- Paid time off
- Medical insurance
- Dental insurance
- Vision insurance
- 401(k)
- Bonus/incentive pay
Company overview
Danaher Corporation is a leading global science and technology innovator headquartered in Washington, D.C., specializing in biotechnology, life sciences, and diagnostics. Founded in 1984 by brothers Steven and Mitchell Rales, the company has evolved from its origins as a manufacturing conglomerate into a premier healthcare technology organization with approximately 63,000 employees worldwide. Danaher operates through three core divisions: biotechnology (28% of revenues), which develops products for therapeutic development; life sciences (31% of revenues), focused on disease identification, new therapies, and drug testing/manufacturing; and diagnostics (41% of revenues), providing instruments, consumables, and software for disease diagnosis. The company's portfolio includes renowned brands such as Beckman Coulter, Cytiva, Pall Corporation, Cepheid, Leica Microsystems, and Abcam, serving pharmaceutical companies, biotechnology firms, healthcare providers, and research institutions globally. Danaher is distinguished by its Danaher Business System (DBS), a continuous improvement methodology that drives innovation and operational excellence. With 2024 revenues of $23.9 billion, the company ranks 180th on the Fortune 500 and plays a critical role in advancing scientific research, improving diagnostic capabilities, and accelerating the development of life-saving therapies.