UNIV - Research Specialist I - Pharmacology and Immunology
MUSC Health
Summary
The Nozaki lab at MUSC aims to uncover fundamental understanding of intestinal immunity during infection and inflammation, focusing on cell death and its associated pathways. The lab also aims to elucidate how intestinal inflammation affects tumor evolution and its microenvironment, and how those mechanisms can be applied to therapeutics. The lab develops novel mouse models and organoid models to analyze complicated death signaling and cell-to-cell, host-pathogen interactions.
Job description
Job Description Summary
The Nozaki lab at MUSC aims to uncover fundamental understanding of intestinal immunity during infection and inflammation, focusing on cell death and its associated pathways. The lab also aims to elucidate how intestinal inflammation affects tumor evolution and its microenvironment, and how those mechanisms can be applied to therapeutics. The lab develops novel mouse models and organoid models to analyze complicated death signaling and cell-to-cell, host-pathogen interactions.
Under the direct supervision of the Principal Investigator, a Research Specialist I is needed to support immunology research for the analysis of mouse gut tissues and cells. Responsible for mouse maintenance, mouse sample preparation and analysis for PCR/qPCRs, Western Blots, flow cytometry, immunofluorescence, maintaining instrumentation and laboratory resources. Having experience of those techniques is a plus, but not necessarily required. The lab can provide various training opportunities.
Job Description
- 30% Performs preparation of mouse tissues for analysis. This includes mouse dissection / tissue harvesting, histopathology analysis, cell culture, molecular cloning, cell transfection / infection, quantitative real time PCR, Western blot, immunostaining, microscopy, and flow cytometry.
- 20% Performs mouse colony maintenance including mouse breeding, genotyping.
- 15% Maintains laboratory equipment by performing checklist systems suitability and required maintenance.
- 15% Assist in ordering reagents and laboratory supplies, and keeping the lab safe, clean and compliant by maintaining a neat work space, wearing appropriate personal protective equipment, and helping with labeling and inspection of laboratory items and solutions.
- 10% Maintain a detailed notebook of experiments performed and location of where data is stored.
- 10% Assist in preparing grant writing and IACUC protocols and amendments when appropriate.
Preferred Qualifications
A bachelor's degree in immunology, or molecular/cell biology.
Minimum Training and Experience Requirements
A high school diploma and two years work experience in a clinical or research setting; a bachelor's degree in chemistry, biology, or other natural, life or health care science may be substituted for the two years of required experience.
Requirements
- High school diploma and two years work experience in a clinical or research setting, or a bachelor's degree in chemistry, biology, or other natural, life or health care science in lieu of experience
- Preferred: bachelor's degree in immunology, or molecular/cell biology
- Experience with PCR/qPCR, Western blots, flow cytometry, immunofluorescence is a plus but not required
Company overview
MUSC Health is the healthcare system of the Medical University of South Carolina, serving as the state's premier academic medical center and comprehensive healthcare provider. Founded in 1824 and headquartered in Charleston, South Carolina, MUSC Health operates 14 hospitals with approximately 2,500 beds and has five additional hospital locations in development. The organization provides patient care through more than 350 telehealth sites and nearly 750 care locations across all regions of South Carolina, serving 46 counties throughout the state. For 11 consecutive years, U.S. News & World Report has ranked MUSC Health as the number one hospital in South Carolina, reflecting its commitment to clinical excellence and patient safety. As an integrated academic health system, MUSC Health combines clinical care with medical education and research, training more than 900 residents and fellows annually while conducting groundbreaking research with $360 million in research funding and 1,268 active clinical trials. The organization employs over 10,000 team members and handles approximately 3.21 million patient encounters each year, delivering specialized services in cancer care, cardiac services, digestive health, women's health, and numerous other medical specialties through its Hollings Cancer Center and other specialized institutes.